Antioxidant properties of ethanol extract of Silybum marianum (milk thistle) seeds was investigated. We have also investigated the protein damage activated by oxidative Fenton reaction and its prevention by Silybum marianum seed extract. Antioxidant potential of Silybum marianum seed ethanol extract was measured using different in vitro methods, such as lipid peroxidation, 1,1-diphenyl-2-picryl...

Milk thistle is a well known and commonly used herb, used particularly in hepatic diseases. It has very potent antioxidant, anti-inflammatory, and antifibrotic properties (1). As a single agent its therapeutic effects in liver disease appear to be modest (2,3,4,5). Herbal medicines and supplements are likely to be much more beneficial when used synergistically in combinations or formulas. Milk ...

The flavolignans silybin (1) and 2,3-dehydrosilybin (2) (Figure 1) were isolated from fruits of milk thistle [Silybum marianum (L). Gaertn.] cultivated in the Samara region (Russian Federation). 2,3-dehydrosilybin (2) for the first time in Russian Federation is described for the given plant. Silybin and 2,3-dehydrosilybin and also new preparation, a fluid extract of Silybum marianum fruits, hav...

background and objectives: milk thistle (silybum marianum), a medicinal plant of the asteraceae family that have been used long time ago, in the treatment of liver disease. sowing date of this plant has not been determined, therefore, this study was necessary. this plant was identified as a weed, this plant is identified as a weed, while silymarin in the seeds are used in the anti-hepatitis and...

Silybum marianum Gaertn., commonly known as milk thistle, seeds of which yield 'silymarine' a flavanoid, has marked antihepatotoxic properties. It is being collected in larger quantities by the pharmaceuticals. There is a great need to cultivate this plant for the sustained supply of the seeds. A package of agrotechnology of the crop is reported in this paper.

Milk Thistle, Silybum marianum Gaertn. plant has been used for centuries as a natural remedy for several diseases. Its active constituent, silymarin displays several medicinal properties, viz. antioxidant, hepatoprotective, cytoprotective, amelioration of hepatic collagen accumulation in advanced fibrosis, immunomodulatory activity, etc. Present paper summarizes various research reports on the ...

Silymarin is the active constituent of Silybum marianum (milk thistle) which is a C-25 containing flavonolignan. Milk thistle has a lot of traditional values, being used as a vegetable, as salad, as bitter tonic, and as galactogogue in nursing mothers and in various ailments such as liver complications, depression, dyspepsia, spleenic congestions, varicose veins, diabetes, amenorrhea, uterine h...

Milk thistle (Silybum marianum (L.) Gaertn.) is one of the valuable medicinal plants which used in the treatment of liver disorders. The major active constituents in this plant are flavonolignans, collectively known as silymarin which is a mixture of three isomer silybin, silydianin and silycristin. Its therapeutic properties are due to the presence of silymarin. The seeds contain the highest a...

Milk thistle (Silybum marianum) extracts are widely used as a complementary and alternative treatment of various hepatic conditions and a host of other diseases/disorders. The active constituents ofmilk thistle supplements are believed to be the flavonolignans contained within the extracts. In vitro studies have suggested that some milk thistle components may significantly inhibit specific cyto...