α-amylase has been studied extensively from various sides. this enzyme is used in many industries .many applications of this enzyme have encouraged us for greater attempts on the study of α-amylase and to search for more effective processes. in this investigation, the structure of nanotube - catalytic site of bacillus subtilis α- amylase was optimized by hyperchem 7.0 and then it was investigat...

Twenty six α-substituted N₄-acetamide derivatives of ciprofloxacin (CIPRO) and norfloxacin (NOR) were synthesized and assayed for antibacterial activity against Pseudomonas aeruginosa, Escherichia coli, Staphylococcus aureus and Bacillus subtilis. The derivatives were primarily more active against Gram-positive bacteria. The CIPRO derivatives, CD-7 (Ar = 3-chlorophenyl), CD-9 (Ar = 2-pyrimidyl)...

BACKGROUND Alkaline α-amylases have potential applications for hydrolyzing starch under high pH conditions in the starch and textile industries and as ingredients in detergents for automatic dishwashers and laundries. While the alkaline α-amylase gains increased industrial interest, the yield of alkaline α-amylases from wild-type microbes is low, and the combination of genetic engineering and p...

Bacillus amyloliquefaciens CB1 was isolated from cheonggukjang, a Korean fermented soy food. B. amyloliquefaciens CB1 secretes proteases with fibrinolytic activities. A gene homologous to aprE of Bacillus subtilis, aprECB1, was cloned from B. amyloliquefaciens CB1, and DNA sequencing showed that aprECB1 can encode a prepro-type serine protease consisting of 382 amino acids. When aprECB1 was int...

BACKGROUND The microbial cell factory Bacillus subtilis is a popular industrial platform for high-level production of secreted technical enzymes. Nonetheless, the effective secretion of particular heterologous enzymes remains challenging. Over the past decades various studies have tackled this problem, and major improvements were achieved by optimizing signal peptides or removing proteases invo...

Fermented succulent shoots of bamboo (Bambusa balcooa and Dendrocalamus strictus) are an enriched source of phytosterol. Microorganisms from the ‘soibum exudate’ involved in microbial bioconversion of phytosterol during fermentation of succulent bamboo shoots were isolated and identified as Bacillus subtilis, B. licheniformis, B. coagulans and Micrococcus luteus. Crude phytosterol was purified ...

There are many studies on the effects of probiotics on performance of broiler chickens, but none of them has evaluated the metabolizable energy (ME) equivalency values of probiotics. The aim of this study was to determine the metabolizable energy equivalency value of Bacillus subtilis spore and its potential for decreasing feed ME content and cost. One hundred seventy-six day-old male broilers ...

background: the effect of several probiotics on diseases of the gastrointestinal tract, including gastric ulcers is well reported. however, there are limited numbers of studies assessing the impact of bacillus subtilis (b. subtilis) probiotic on skin wound healing. m aterials and methods: fifty male rats were assigned to 3 different groups randomly. a 1.5 cm longitudinal full thickness incision...