background: there are only a very small number of reports which discuss subtype, sex distribution, clinical features and laboratory characteristics of autoimmune hepatitis in children. the aim of this study was both to define the clinical features, biochemical and histological findings and also to determine the age and sex related distribution of autoimmune hepatitis (aih). materials and method...

background: celiac disease (cd) has been found in up to 10% of the patients presenting with unexplained abnormal liver function tests (lft). as there is no precise data from our country in this regard, we investigated the prevalence of cd in patients presenting with abnormal lft. methods: from 2003 to 2008, we measured iga anti-tissue transglutaminase (t-tg) antibody (with elisa technique) with...

background: autoimmune hepatitis (aih) in childhood has variable modes of presentation, and the disease should be suspected and excluded in all children presenting with symptoms and signs of prolonged or severe acute liver disease. in aih, the liver biopsy histopathology shows inflammation in addition to presence of serum autoimmune antibodies and increased levels of immunoglobulin g (igg). obj...

Background: Autoimmune hepatitis (AIH) in childhood has variable modes of presentation, and the disease should be suspected and excluded in all children presenting with symptoms and signs of prolonged or severe acute liver disease. In AIH, the liver biopsy histopathology shows inflammation in addition to presence of serum autoimmune antibodies and increased levels of immunoglobulin G (IgG). Ob...

Background Chronic liver diseases (CLD) in children represent a growing health problem with significant morbidity and mortality. This study aimed to define the clinicopathological pattern of pediatric CLD in Sohag University Hospital, Sohag,Upper Egypt. Materials and Methods A total of 151children with CLD were included in a prospective hospital-based study from June 2014 to May 2018. Cases of...

aim : we described two case reports of aih/ssc overlap syndrome and reviewed literatures regarding this issue.   background : aih is a chronic hepatitis of unknown aetiology characterized by continuing hepatocellular necrosis and inflammation. aih overlap syndromes have been reported with other autoimmune diseases. patients and methods : according to the classification criteria for ssc, we cond...