Large portions of the Great Plains and the western U.S. are regularly plagued by drought and diminishing water resources for irrigation. Alfalfa cultivars adapted to these regions, and that can remain productive under reduced irrigation allotments, are clearly needed. This study evaluated the potential of using DNA marker assisted selection (MAS) technology to improve alfalfa forage productivit...

pyramiding genes related to grain quality and resistance through marker assisted selection (mas) is an important approach in rice breeding programs. marker-assisted selection can be used for monitoring the presence or absence of these genes in breeding populations and can be combined with conventional breeding approaches. this study is a part of cultivar development program in iran through inte...

potato virus y (pvy) is one of the most important pathogenic agents that reduce the yield and quality of tobacco (nicotiana tabacum l.). dna-based molecular markers are valuable tools for identifying germplasm in gene banks, assessing kinship ties, and doing marker-assisted selection (mas) for resistance to pests, diseases, and some crop traits of interest. this work presents the results of ass...

Calpastatin is an endogenous inhibitor of calpain (calcium-dependent cysteine protease). Calpastatin activityis highly related to the rate of protein turnover and rate of meat tenderization. In order to characterize thestructure of calpastatin in Iranian Afshari breed of sheep, intron 6 and partial exon 7 of the L domain wereamplified and sequenced. A fragment of approximately...

The change from a Mendelian to a genomic breeding paradigm poses three challenges: to map the components of animal breeding onto a genomic conceptual frame work; to show how the genetic parameters comprising a genomic analysis can be obtained from actual farm data; and to show how genomic parameters can guide a breeding program. We are currently heavily engaged in the second challenge, but shou...

Effect of flanking quantitative trait loci (QTL)-marker bracket size on genetic response to marker assisted selection in an outbred population was studied by simulation of a nucleus breeding scheme. In addition, genetic response with marker assisted selection (MAS) from two quantitative trait loci on the same and different chromosome(s) was investigated. QTL that explained either 5% or 10% of p...

Marker-Assisted-Selection (MAS) is mainly important in situations, where the current accuracy of selection is low, e.g. traits with low heritability, limited, late-in-life, or afterslaughter recording. In veloand whizzo genetics schemes, the number of selection cycles per time period is minimized, which may increase rates of genetic gain dramatically. Genomic selection is used to obtain a high ...

A deterministic two-loci model was developed to predict genetic response to marker-assisted selection (MAS) in one generation and in multiple generations. Formulas were derived to relate linkage disequilibrium in a population to the proportion of additive genetic variance used by MAS, and in turn to an extra improvement in genetic response over phenotypic selection. Predictions of the response ...

Computer simulations were used to study the efficiency of marker-assisted selection (MAS) based on an index combining the phenotypic value and the molecular score of individuals. The molecular score is computed from the effects attributed to markers by multiple regression of phenotype on marker genotype. The results show that in the first generation the ratio RE of the expected efficiency of MA...