Arzoxifene (ARZ) is a selective estrogen receptor (ER) modulator with greater bioavailability than raloxifene which is being developed as treatment for breast cancer. We have used an in vivo model of hormone-sensitive breast cancer to study the growth-inhibitory and pharmacodynamic effects of ARZ in comparison with the most widely used antiestrogen, tamoxifen (TAM). We compared the abilities of...

The many differences between Dialectal Arabic and Modern Standard Arabic (MSA) pose a challenge to the majority of Arabic natural language processing tools, which are designed for MSA. In this paper, we retarget an existing state-of-the-art MSA morphological tagger to Egyptian Arabic (ARZ). Our evaluation demonstrates that our ARZ morphology tagger outperforms its MSA variant on ARZ input in te...

We revisit the entropy formulation and the wave-front tracking construction of physically admissible solutions of the Aw-Rascle and Zhang (ARZ) “second-order” model for vehicular traffic. A Kruzhkov-like family of entropies is introduced to select the admissible shocks. This tool allows to define rigorously the appropriate notion of admissible weak solution and to approximate the solutions of t...

Translation of Reun ar C'halan [René Galand] " Baudelaire, diouganer an arz nevez " , Al Liamm, niv.

Recently Aw, Rascle and Zhang introduced a second order model (ARZ) that does nor exhibit the usual drawbacks of this family of models, i.e. negative velocities and/or densities. In this paper we analyze the inhomogeous Riemann problem for this model, which is shown to be equivalent to the inhomogeous Riemann problem for a related first order model with modified equilibrium flow density relatio...

Ninety-six patients with recurrent, drug-refractory tachyarrhythmias were treated with amiodarone for 8.0 + 7.5 months (range 1 day to 27 months): 77 for recurrent ventricular tachycardia or ventricular fibrillation (VT/VF), two for complex ventricular ectopy, and 17 for supraventricular tachyarrhythmias. The actuarial incidence of successful amiodarone therapy was 52 + 7% at 12 months and 28 +...

Objectives: The rapid diagnosis and early risk stratification of patients presenting with acute myocardial infarction (AMI) is important. In experimental setting ultrasonic strain rate (SR) and strain (S) have been shown to identify changes in deformation predictive of ischemia. We sought to evaluate and compare regional myocardial function at “the risk zone” (ARZ) supplied by the culprit coron...

Lower bounds for the condition numbers of the preconditioned systems are obtained for two-level additive S c h w arz preconditioners for both second order and fourth order problems. They show that the known upper bounds are sharp in the case of a small overlap.

Let F (Z) = P r arZ r be a rational generating function in the d variables Z1, . . . , Zd. Asymptotic formulae for the coefficients ar may be obtained via Cauchy’s integral formula in Cd. Evaluation of this integral is not as straightforward as it is in the univariate case. This paper discusses geometric techniques that are needed for evaluation of these integrals and surveys classes of functio...