the present study explores the chemical constitution and antioxidant activity of the essential oils of the aerial parts of artemisia dracunculus l. and the flower heads of matricaria chamomilla l. gc-ms analysis revealed the presence of (z)-anethole (51.72%), (z)-β-ocimene (8.32%), methyleugenol (8.06%), limonene (4.94%) and linalool (4.41%) in artemisia dracunculus and (e)-β-farnesene (24.19%)...

Aim & Objective. Artemisia dracunculus L. (Tarragon) species have been used as a traditional medicine. The present study was designed to evaluate the nociceptive and anti-inflammatory effects of A. dracunculus L. leaf aqueous extract on fructose drinking water (FDW) in male rats. Materials & Methods. Forty-eight Wistar-albino male rats weighing 200-250 g were divided into control (C), control e...

Two effective cytochrome P450 (CYP) inhibitors were isolated from tarragon, Artemisia dracunculus. Their structures were spectroscopically identified as 2E,4E-undeca-2,4-diene-8,10-diynoic acid isobutylamide (1) and 2E,4E-undeca-2,4-diene-8,10-diynoic acid piperidide (2). Both compounds had dose-dependent inhibitory effects on CYP3A4 activity with IC50 values of 10.0 ± 1.3 µM for compound 1 and...

The essential oil isolated from Turkish tarragon (Artemisia dracunculus) by hydrodistillation was analyzed by GC-MS. Thirty compounds representing 99.5% of total oil were identified. The predominant components in the oil were (Z)-anethole (81.0%), (Z)-beta-ocimene (6.5%), (E)-beta-ocimene (3.1%), limonene (3.1%), and methyleugenol (1.8%). The antibacterial and antifungal activities of the essen...

methods the mice were divided into six groups including a normal control group, a placebo group, and three treatment groups receiving 50, 100, and 200 mg/kg doses of hydroalcoholic extract via intraperitoneal (ip) injection followed by inoculation with c. albicans. a control+ group, inoculated only with c. albicans, was also employed. after all treatments, the mice were killed by cervical decap...

Background and purpose: The status of medicinal plants in Iranian traditional medicine and rich existence of herbal sources, on one hand, and current problems in curing infections, on the other hand, are the factors to study medicinal plants more accurately. Tarragon (Artemisia dracunculus L.) is a herbaceous plant from Asteraceae family, available in planted and farming forms in Iran. This stu...

BACKGROUND Leishmaniasis is a parasitic disease that appears with a range of symptoms including cutaneous, mucocutaneous, and visceral leishmaniasis. The present study sought to determine the antileishmanial effect of the extract of Artemisia dracunculus (Tarragon) compared to control treatment with pentavalent antimony (meglumine). METHODS This experimental study was performed in 2014-2015. ...

Artemisia dracunculus L. (tarragon) has a long history of use as a spice and remedy. Two well-described "cultivars" (Russian and French) are used widely and differ in ploidy level, morphology, and chemistry. Key biologically active secondary metabolites are essential oils (0.15-3.1%), coumarins (>1%), flavonoids, and phenolcarbonic acids. In vivo studies mainly in rodents, particularly from Ru...