neuroinflammation is inflammation of the nervous tissue. it be initiated in response to infection, toxic metabolites, auto immunity, traumatic brain injury and variety of causes. exercise is a promising mechanism of prevention and treatment for disease characterized by neuroinflammation. the benefits of exercise and physical activity (pa) are well known and have effects on function of the centr...

leptadenia reticulata was reported to be used for several medicinal purposes. the present study was undertaken to evaluate anti-inflammatory, analgesic and lipid peroxidation inhibition activities of l. reticulata. the anti-inflammatory assay was performed by λ-carrageenan and formalin induced paw edema test. pro inflammatory mediators (il2, il6, tnf-α) in serum of treated and control organism ...

neovascularization of the normally avascular cornea was associated with a notable increase in the expression of the major pro-angiogenic factors, inflammatory cytokines and proteases. the data supporting a causal role for vascular endothelial growth factor (vegf), inflammatory cytokines and matrix metalloproteinase (mmps) are extensive. anti-angiogenic/anti-inflammatory therapy is considered as...

Many complicated mechanisms are involved in brain ischemia and the role of inflammatory factors in the progression of post-ischemic injury is inevitable. In present study, anti-inflammatory effect of berberine has been investigated in reperfusion injury after acute ischemic stroke. Male Wistar rats weighing 250-270 gr were randomly divided into four cohorts: healthy rats (control, n=20), sham-o...

background: ghrelin is a peptide with attenuating effect on inflammatory pain. both anti- and pro-inflammatory mediators have a role in the nociception and development of pain and hyperalgesia. il-10 and tgf-β are anti-inflammatory cytokines and inhibit the expression of pro-inflammatory cytokines related to peripheral and central inflammatory pain. in this study, the effects of i.p. injection ...

context inflammatory pains caused by direct stimulation of nociceptors are altered by release of inflammatory mediators, cytokines and chemokines and also gut microbiota. a substantial clinical evidence supports the pivotal role of probiotics in the betterment of inflammatory disorders symptoms such as pain. therefore, this study aimed to review the potential anti-inflammatory and analgesic rol...

Background: Ghrelin is a peptide with attenuating effect on inflammatory pain. Both anti- and pro-inflammatory mediators have a role in the nociception and development of pain and hyperalgesia. IL-10 and TGF-β are anti-inflammatory cytokines and inhibit the expression of pro-inflammatory cytokines related to peripheral and central inflammatory pain. In this study, the effects of i.p. injec...