Sestrin (SESN) is known as a cysteine sulfinic acid reductase. Recently, nonredox functions of SESN in metabolic regulation and antitumor property have been recognized. While mechanisms underlying the expression of SESN are not fully understood. Here we report that insulin markedly increased SESN2 level in HepG2 cells through mTOR activation. To determine whether insulin affects SESN2 degradati...

In particular, chalcogenide glasses and glass-ceramics are new materials that exhibit good transparency in infrared region (0.8-12µm). We can overcome the main weakness of these glasses by improving the hardness through controlling crystallization. In this paper, we report results of a study on chalcogenide glasses in the ternary system of As-Se-Ge with nominal composition of Snx (Se...

Synthetic routes to salts of the 3H-naphtho[1,2-d][1,2,3]dithiazolylium cation and its three selenium-containing variants (SSeN, SeSN, and SeSeN) are described. The most efficient and general method involves the intermediacy of bis-acetylated aminothiolates and aminoselenolates. These reagents react smoothly with sulfur and selenium halides to afford the desired ring closure products. Electroch...

Sestrins are stress-inducible metabolic regulators with two seemingly unrelated but physiologically important functions: reduction of reactive oxygen species (ROS) and inhibition of the mechanistic target of rapamycin complex 1 (mTORC1). How Sestrins fulfil this dual role has remained elusive so far. Here we report the crystal structure of human Sestrin2 (hSesn2), and show that hSesn2 is twofol...

Highly enantioselective and good to high-yielding aziridination of conjugated and non-conjugated terminal olefins and cyclic olefins was achieved using a newly designed Ru(CO)(salen) complex as the catalyst in the presence of SESN(3) under mild conditions.

zno and zno: mn nanocrystals were synthesized via reverse micelle method. the structural properties of nanocrystals were investigated by xrd. the xrd results indicated that the synthesized nanocrystals had a pure wurtzite (hexagonal phase) structure. resistive gas sensors were fabricated by providing ohmic contacts on the tablet obtained from compressed nanocrystals powder and the installation ...

ZnO and ZnO: Mn nanocrystals were synthesized via reverse micelle method. The structural properties of nanocrystals were investigated by XRD. The XRD results indicated that the synthesized nanocrystals had a pure wurtzite (hexagonal phase) structure. Resistive gas sensors were fabricated by providing ohmic contacts on the tablet obtained from compressed nanocrystals powder and the installation ...

the aim of this study was to investigate the barrier properties of cellulose nanocrystals-pvananocomposites. nanocomposite films with different filler loading levels (3, 6, 9 and 12% by wt) weredeveloped by solvent casting method. the effect of cellulose nanocrystals on the barrier properties ofthe nanocomposites was studied. to this end, moisture absorption, water vapor permeability (wvp),oxyg...

ZnO and ZnO: Mn nanocrystals were synthesized via reverse micelle method. The structural properties of nanocrystals were investigated by XRD. The XRD results indicated that the synthesized nanocrystals had a pure wurtzite (hexagonal phase) structure. Resistive gas sensors were fabricated by providing ohmic contacts on the tablet obtained from compressed nanocrystals powder and the installation ...

In this study, colloidal germanium nanocrystals were synthesized by a simple and novel method, and their optical properties were also studied. Polyvinyl alcohol (PVA) as a surface modifier was used to control the optical properties of colloidal Ge nanocrystals. Fourier transform infrared spectroscopy (FTIR) analysis was performed to identify the various functional groups present in the sample. ...