summary: adult-onset still’s disease (aosd) is a rare systemic inflammatory disorder of unknown etiology. it is characterized by high grade fever, skin rash, arthritis, leukocytosis, increased esr, crp and liver enzyme levels and high levels of ferritin. the treatment of aosd includes nsaids, steroids, and disease-modifying antirheumatic drugs (dmards). recently biologic agents have been used f...

adult-onset still’s disease (aosd) is a rare systemic inflammatory disorder of unknown etiology. there is not currently any specific serological markers for aosd , and  diagnosis still relying on the exclusion of other likely diagnoses. yamaguchi’s criteria are used as a diagnostic criterion which contains negative serologic markers for other collagen vascular diseases including systemic lupus ...

background familial mediterranean fever (fmf) is an autosomal recessive disorder characterized by sporadic, paroxysmal attacks of fever and serosal inflammation. although the disease usually begins before the age of 20 years, we aimed to evaluate the demogra­phy, clinical features and treatment outcome of familial mediter­ranean fever in iranian adult patients above 20 years old. methods in thi...

the clinical behavior of asthma varies with age at onset. this study was undertaken to identify associated markers of adult-onset allergic asthma (age ≥20 years).this cross-sectional study compared two groups: 58 patients with asthma onset at <20 years and 66 with onset at ≥20 years. they were compared depending on results of clinical history, and body mass index (bmi), aeroallergen sensitizati...