the adaptive response (ar) is a phenomenon by which cells exposure to sublethal doses of dna-damaging agents (non-mutagenic dose of chemical or radiation), known as conditioning treatment (ct), leads to increased resistance to a subsequent exposure to a higher dose of the same or other agents, known as challenge treatment (cr). the adaptive response (ar) induced by radiation in human lymphocyte...

The adaptive response (AR) is a phenomenon by which cells exposure to sublethal doses of DNA-damaging agents (non-mutagenic dose of chemical or radiation), known as conditioning treatment (CT), leads to increased resistance to a subsequent exposure to a higher dose of the same or other agents, known as challenge treatment (CR). The adaptive response (AR) induced by radiation in human lymphocyte...

Prior work has provided incremental phases to a microdosimetry modeling program to describe the dose response behavior of the radio-protective adaptive response effect. We have here consolidated these prior works (Leonard 2000, 2005, 2007a, 2007b, 2007c) to provide a composite, comprehensive Microdose Model that is also herein modified to include the bystander effect. The nomenclature for the m...

background: drug resistance is widely believed to be an increasingly serious threat to global public health. we have previously reported that short term exposure of microorganisms to diagnostic ultrasound waves could significantly alter their sensitivity to antibiotics. in our previous studies, klebsiella pneumoniae showed major differences in the sensitivity to antibiotics in exposed and non-e...

Although androgen receptor (AR) pathway inhibitors prolong survival in castrate-resistant prostate cancer (CRPC), resistance rapidly develops and is often associated with increased stress-activated molecular chaperones like clusterin (CLU) and continued AR signaling. Because adaptive pathways activated by treatment facilitate development of acquired resistance, cotargeting the stress response, ...

background: mobile phones, use electromagnetic radiation in the microwave range. on the other hand, there is only one report on radioprotective effects of flaxseed oil. the aim of this study was to investigate the effect of irradiation of rats with microwaves and/or treatment with flaxseed oil on the induction of adaptive response to a subsequent lethal dose (ld) of gamma rays. materials and me...

in this paper, we deal with the problem of adaptive coherent signal detection in gaussian interference (clutter plus noise) for surveillance pulse radars. some of the adaptive radar detectors exploit the ar model for clutter. most of these detectors have been obtained using the glr test. this test relies on the maximum likelihood estimation whose accuracy depends on the number of data. whereas,...

introduction: advanced oxidation processes (aops) suggest a highly reactive, nonspecific oxidant namely hydroxyl radical (oh•), that oxidize a wide range of pollutants fast and non-selective in wastewater and water. materials and methods: in this work, the nitrogen-doped titanium dioxide nanoparticles were primed by sol-gel method, characterized by x-ray diffraction and scanning electron micros...

The aim of this preliminary investigation was to assess whether human peripheral blood lymphocytes which have been pre-exposed to non-ionizing radiofrequency fields exhibit an adaptive response (AR) by resisting the induction of genetic damage from subsequent exposure to ionizing radiation. Peripheral blood lymphocytes from four healthy donors were stimulated with phytohemagglutinin for 24 h an...

background: radio-adaptive response and bystander effects are known phenomena occurring in cells following exposure to ionizing radiation (ir). in this study we examined possible radio-adaptation of lymphocytes following bystander effects induced by cho-k1 cells. materials and methods: whole blood and cho-k1 cells were cultured in rpmi-1640 complete medium. cells were separately irradiated with...