background and aims. recent epidemiological studies have shown that individuals with periodontitis have a significantly higher risk of developing coronary heart disease, which might be attributed to the complex microbiota in the dental plaque. periodontopathogens have been reported as risk factors for cardiovascular disease. this study evaluated association of chronic periodontitis and periodon...

background. this study was designedaimed to investigate assess the antimicrobial antimicrobial eeffect of chlorhexidine (chx) on aggregatibacter a. actinomycetemcomitans biofilmss extracted isolated from subgingival plaque of periperi-iimplantitis lesions. methods. 13 thirteen participants patients requiring peri-implantitis treatment were consecutively selected and theirwere consecutively recr...

Crude Flavonoids extracted from crushed seeds of dried ripe fruits Solanum surattense Burm F. were screened for antimicrobial activity against two bacteria – Streptococcus mutans and Aggregatibacter actinomycetemcomitans which found to be major contributers occurrence Dental caries. Minimum inhibitory concentration, bactericidal Time Kill curve the extract each sensitive test pathogen, evaluate...

This study examined in vivo and in vitro colonization by Aggregatibacter actinomycetemcomitans, an organism highly associated with aggressive periodontitis. Thirteen volunteers (5 were A. actinomycetemcomitans positive for buccal epithelial cells [BECs] and teeth, 5 were A. actinomycetemcomitans positive for teeth only, and 3 were A. actinomycetemcomitans-negative controls) had two mandibular s...

Aggregatibacter actinomycetemcomitans is frequently associated with localized aggressive periodontitis (LAP); however, longitudinal cohort studies relating A. actinomycetemcomitans to initiation of LAP have not been reported. A periodontal assessment was performed on 1,075 primarily African-American and Hispanic schoolchildren, ages 11 to 17 years. Samples were taken from each child for A. acti...

introduction: considering the importance of prevention in periodontal diseases and the important role of aggregatibacter actinomycetemcomitans in induction and progression of these diseases, the aim of the present in vitro study was to compare the antimicrobial effects of chlorhexidine digluconate (chx), curcumin and light-emitting diode (led) laser, on this bacterium. methods: antimicrobial ac...

Actinobacillus actinomycetemcomitans, a periodontal pathogen, has been strongly implicated in human periodontal disease. Advances in the molecular analysis of A. actinomycetemcomitans virulence factors have been limited due to the unavailability of systems for genetic transfer, transposon mutagenesis, and gene complementation. Slow progress can be traced almost exclusively to the lack of gene v...

Our previous report has shown that Irsogladine maleate (IM) counters and obviates the reduction in gap junction intercellular communication (GJIC) and the increase in IL-8 levels, respectively, induced by outer membrane protein 29 from Actinobacillus actinomycetemcomitans (A. actinomycetemcomitans) in cultured human gingival epithelial cells (HGEC). In addition, IM suppresses the increase in th...