BACKGROUND Embryo quality may be accurately assessed as early as the pronuclear zygote phase, as shown in recent studies. However, it is not known whether good quality zygotes are destined to become good quality cleavage stage embryos and blastocysts. METHODS In this retrospective study, 86 intracytoplasmic sperm injection-embryo transfer cycles were studied where each available embryo was sc...

BACKGROUND Embryos selection is crucial to maintain high performance in terms of pregnancy rate, reducing the risk of multiple pregnancy during IVF. Pronuclear and nucleolar characteristics have been proposed as an indicator of embryo development and chromosomal complement in humans, providing information about embryo viability. METHODS To correlate the zygote-score with the maternal age and ...

Background: Digital image processing and analysis are used for computer assisted evaluation of sperm morphology. Sperm head morphology has been identified as a characteristic that can be used to predict a male’s semen quality. On the other hand, zygote competence analysis is an importance tool to select embryo(s) for transfer. The aim of the present study is to determine zygote quality resulted...

introduction: pronuclear size, morphology and orientation are known to affect embryo quality and implantation. the present study was aimed at evaluation of the possible relationship between protamine deficiency with pronuclear morphology and also cleavage and embryo quality. material and methods: semen sample of 160 candidate icsi and ivf couples were analyzed for sperm concentration, and motil...

The current systematic review was aimed to assess the effectiveness of the zygote morphology evaluation in fresh in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) cycles. All available studies reporting on zygote morphology and clinical and/or biological outcomes were analyzed. Forty studies were included in the final analysis. Fourteen different zygote scoring systems we...

Embryo culture can serve as a strong diagnostic tool, yielding useful information regarding the implantation potential of the human embryo. The information thus gained is useful for quality control of the embryology laboratory, success rates of the IVF/intracytoplasmic sperm injection (ICSI) programme, and counselling of the couple following failed cycles. Zygotes can be scored and zygote quali...

BACKGROUND A scoring system has been developed to determine preimplantation embryo quality, and used to select embryos for transfer into the uterus of patients. METHODS AND RESULTS The system was used to study early embryo development and to test whether these scores alone can accurately predict IVF outcome. Following zygote and embryo scores through early development, the data showed that a ...

background: multiple factors have been suggested for prediction of pregnancy in intracytoplasmic sperm injection (icsi) cycles such as the number of injected oocytes, fertilization rate, embryo morphology and quality of transferred embryos. predictive value of these factors is important in icsi outcome. objectives: to evaluate the role of embryo morphology for prediction of pregnancy in icsi cy...

BACKGROUND Many factors from the oocyte/sperm or the process of fertilization may affect the zygote formation. The zygote score (Z-score) describes the quality of a human zygote based on its pronuclear morphology, nucleolar precursor bodies, and alignment of polar bodies, and it can be used in the selection process at the zygote stage for embryo transfer or cryopreservation. OBJECTIVE The aim...