Zingiber officinale Roscoe has been widely used as a folk medicine to treat various diseases, including cancer. This study aims to re-examine the therapeutic potential of co-administration of natural products and cancer chemotherapeutics. Candidate material for this project, α-zingiberene, was extracted from Zingiber officinale Roscoe, and α-zingiberene makes up 35.02 ± 0.30% of its total essen...

Casearia sylvestris (Salicaceae), popularly known as "guaçatonga", is a plant widely used in folk medicine to treat various diseases, including cancer. The present work deals with the chemical composition as well as the cytotoxic evaluation of its essential oil, its main constituent and derivatives. Thus, the crude essential oil from leaves of C. sylvestris was obtained using a Clevenger type a...

alpha-Zingiberene synthase (ZIS), a sesquiterpene synthase gene that was isolated from lemon basil (Ocimum basilicum L.), encodes an enzyme that catalyzes the formation of alpha-zingiberene, and other sesquiterpenes, from farnesyl diphosphate. Transgenic tomato fruits overexpressing ZIS under the control of the fruit ripening-specific tomato polygalacturonase promoter (PG) accumulated high leve...

Secretions from glandular trichomes potentially protect plants against a variety of aggressors. In the tomato clade Solanum genus, wild species produce rich source chemical diversity at leaf surface. Previously, 7-epi-zingiberene produced in several accessions habrochaites was found to confer resistance whiteflies (Bemisia tabaci) and other insect pests. Here, we report identification character...

The essential oils of ginger (Zingiber officinale) and turmeric (Curcuma longa) contain a large variety of terpenoids, some of which possess anticancer, antiulcer, and antioxidant properties. Despite their importance, only four terpene synthases have been identified from the Zingiberaceae family: (+)-germacrene D synthase and (S)-β-bisabolene synthase from ginger rhizome, and α-humulene synthas...

Zingiberene is a constituent of Zingiber officinale (L), structurally monocyclic sesquiterpene, and possesses immense pharmacological activity. The present attempt was aimed to utilize methanol solution zingiberene for topical application at forty-eight hours after the fourth molt fifth instared larvae silkworm, Bombyx mori (L) [Race: Double Hybrid - (CSR6 x CSR26) CSR2 CSR27)]. found significa...

ginger plant, zingiber officinale roscoe, is an important tropical plant used as spices and well known for its medicinal properties. it has a pungent and aromatic rhizome rich of zingiberen and gingerols. many secondary metabolites are known to accumulate in the plant cell culture systems. so, in this research, gingerols and zingiberene production of callus cultures were compared with regenerat...

      Ginger plant, Zingiber officinale Roscoe, is an important tropical plant used as spices and well known for its medicinal properties. It has a pungent and aromatic rhizome rich of zingiberen and gingerols. Many secondary metabolites are known to accumulate in the plant cell culture systems. So, in this research, gingerols and zingiberene production of callus cultures were compared...