collagens are the most abundant proteins in the human body. their main function is to provide structural and mechanical support for the tissues, but they are also involved in a number of other biological functions including cell attachment, migration and differentiation. collagens and gelatins are widely used in pharmaceutical and medical applications. every year, more than 50,000 tons of colla...

background: saccharomyces boulardii (s. boulardii) is the best known probiotic yeast. the genetic engineering of this probiotic strain requires the availability of appropriate mutants to accept various gene constructs carrying different selection markers. as the auxotrophy selection markers are under focus, we have generated a ura3 auxotroph mutant of s. boulardii for use in further genetic man...

objective: fungal nail infection (onychomycosis) is a common disease in all communities consisting about 50 percent of nail disorders. yeasts are one of the important causative agents of onychomycosis. identification of the yeast species is important in the epidemiological and therapeutical point of views. the aim of the present study is the precise species identification of the pathogenic yeas...

to accomplish the worldwide demand for recombinant human erythropoietin (rhuepo) as a therapeutic, application of cost-efficient expression system of methylotrophic yeast pichia pastoris (p. pastoris) rather than mammalian cells is indispensable. herein, a report on high levels secreted-expression of pichia-derived rhuepo by batch fermentation in a ph stabilized format is presented. the full le...

background a broad variety of fungi, especially candida species, are becoming increasingly common causes of urinary tract infections in hospital settings. objectives the current cross-sectional descriptive study aimed to determine the causative agents, risk factors and incidence rate of candiduria in critically ill patients, hospitalized in intensive care units (icus) of four iranian hospitals....

When we performed melezitose assimilation test in industrial yeasts, most sake yeasts failed to assimilate melezitose, while the other industrial yeasts could. We therefore tried to elucidate differences for melezitose assimilation among industrial yeasts. Results showed industrial yeasts had no melezitose resolving power on the cell surface, but had this in the cell. Also, the sake yeasts had ...

We divided industrial yeast strains of Saccharomyces cerevisiae into three groups based on the sequences of their internal transcribed spacer (ITS) regions. One group contained sake yeasts, shochu yeasts, and one bakery yeast, another group contained wine yeasts, and the third group contained beer and whisky yeasts, including seven bakery yeasts. The three groups were distinguished by polymorph...

background and purpose: by using advanced detection/identification methods, the list of emerging uncommon opportunistic yeast infections is rapidly expanding worldwide. our aim in the present study was sequence-based species delineation of previously unidentified yeasts obtained from a clinically yeast collection. materials and methods: a total of twenty three out of the 855 (5.7%) yeast isolat...

The use of new transgenic yeasts in industry carries a potential environmental risk because their dispersal, introducing new artificial genetic combinations into nature, could have unpredictable consequences. This risk could be avoided by using sterile transgenic yeasts that are unable to sporulate and mate with wild yeasts. These sterile yeasts would not survive the annual cyclic harvesting pe...