Abstract Background: Considering the fear of drug addicts from hangover symptoms and the costs of withdrawal treatment and their importance in deciding to withdraw, it is helpful to identify various ways of withdrawal and their effects. This study investigated the withdrawal symptoms of two methods of detoxification with clonidine and rapid detoxification of clonidine with naltrexone....

5 An implicit partial differential equation (PDE) method is used to determine the cost of hedg6 ing for a Guaranteed Lifelong Withdrawal Benefit (GLWB) variable annuity contract. In the 7 basic setting, the underlying risky asset is assumed to evolve according to geometric Brownian 8 motion, but this is generalized to the case of a Markov regime switching process. A similarity 9 transformation ...

OBJECTIVE The purpose of this study was to test the hypothesis that treatment of neonatal opiate withdrawal (NOW) in the term infant with diluted tincture of opium (DTO) and phenobarbital was superior to treatment with DTO alone. STUDY DESIGN This was a partially randomized, controlled trial in which 20 term infants exposed to methadone and/or heroin in utero were studied. The severity of NOW...

Are benzodiazepines and anticonvulsants effective for patient with alcohol withdrawal symptoms？(Are anticonvulsants more effective than benzodiazepines？) P: alcohol withdrawal I: benzodiazepines and anticonvulsants C: placebo or active placebo O: prevent or relief alcohol symptoms (ex: delirium, seizure) , prevent re-intake alcohol 關鍵字(Key words): (alcohol withdrawal and benzodiazepine) (alcoho...

OBJECTIVE To compare the real-world, 5-year clinical and cost impact of maintaining treatment with the tumor necrosis factor-α inhibitors (anti-TNFs) adalimumab, etanercept, or infliximab vs dose tapering or withdrawal in rheumatoid arthritis (RA) patients who have achieved remission (defined as a 28-joint count Disease Activity Score [DAS28] < 2.6) or low disease activity (LDA; DAS28 < 3.2). ...

Background: The evidence for the effectiveness and safety of inhaled corticosteroids (ICS) in chronic obstructive pulmonary disease (COPD) is inconclusive. This study determined the cost effectiveness of withdrawing fluticasone propionate (FP) in outpatients with COPD. Methods: The cost effectiveness analysis was based on a randomised, placebo controlled FP withdrawal study. After a 4 month run...

OBJECTIVE To evaluate the effect of acute postoperative alcohol withdrawal on survival of vascularized fibular grafts for mandibular reconstruction. DESIGN Retrospective case series of 17 consecutive patients. MAIN OUTCOMES MEASURE Relation between flap survival and alcohol withdrawal. RESULTS Flap survival rate was 25% for patients who experienced delirium tremens and 85% in the other pa...