background: the aim of this study was to determine the correlation between ultrastructural studies for pinopodes expression after ovarian hyperstimulation and progesterone injection in mice. materials and methods: adult nmri mice were superovulated using human menopasual gonadotropic (hmg) and human chorionic gonadotropic (hcg) hormones; after that, daily injection of progesterone (1 mg/mouse) ...

background: the opening and closing of the implantation window is important for successful pregnancy in eutherians. the recent study demonstrated that the window of uterine receptivity was prepared by the sole action of progesterone in mice, but the mechanism to close the window remained to be elucidated. methods: the pregnant mice were ovariectomized on the evening on the third day of pregnanc...

The endometrium is a highly dynamic tissue empowered with the capacity to undergo cyclic dramatic changes in response to ovarian steroid hormones, ultimately aiming to create a window of receptivity for blastocyst implantation. Intensive research has been performed to understand and establish morphological and molecular correlates of embryo implantation. However, it still remains a biological m...

the success rate of several advanced basic and clinical techniques in the field of mammalian biotechnology, including cloning, pre-implantation genetic diagnosis, and assisted reproductive techniques (art) depends mainly on the success rate of pregnancy following in vitro fertilization-embryo transfer (ivfet). the techniques used in art have advanced considerably since the first in vitro fertil...

background: pinopodes are suggested as biological markers of uterine receptivity, but their molecular components are unknown. objective: co-expression of galectin-3 and ?v?3 integrin at human pinopodes has been examined in this study to propose a role for them during adhesion phase of embryo implantation. materials and methods: biopsies were obtained from early and mid luteal phase endometrium ...

Introduction: In implantation, endometrial epithelium is affected by the release of steroid hormones secreted from the ovary and allows the blastocyst to bind. This course is called the “implantation window” and occurs about 4-10 days after the onset of progesterone secretion. Therefore, the endometrium undergoes changes in the configuration of microvilli in the apical membrane, as well as the ...

To investigate the effect of surgical treatment of hydrosalpinx on the expressions of estrogen receptor (ER) and progesterone receptor (PR) in the endometrium in implantation window, a total of 60 patients with hydrosalpinx and 30 patients with fallopian tube obstruction were recruited. In the implantation window, immnohistochemistry was carried out to detect the expressions of ER and PR in the...

Clinical importance of the improved expressions of integrin αvβ3 and L-selectin ligand in the endometrium following the surgical treatment for hydrosalpinx has been studied. A total of 60 patients with hydrosalpinx and 30 patients with fallopian tube obstruction were recruited. In the implantation window, immnohistochemistry was carried out to detect the expressions of integrin αvβ3 and L-selec...