poliomyelitis (polio) is a highly infectious viral disease, which mainly affects young children. the virus is transmitted by person-to-person spread mainly through the faecal-oral route or, less frequently, by a common vehicle (e.g. contaminated water or food) and multiplies in the intestine, from where it can invade the nervous system and can cause paralysis. initial symptoms of polio include ...

Poliomyelitis (polio) is a highly infectious viral disease, which mainly affects young children. The virus is transmitted by person-to-person spread mainly through the faecal-oral route or, less frequently, by a common vehicle (e.g. contaminated water or food) and multiplies in the intestine, from where it can invade the nervous system and can cause paralysis. Initial symptoms of polio include ...

objective: as we are approaching the global eradication of wild poliovirus, laboratory surveillance of poliovirus by the gold standard cell culture method becomes increasingly important. as there is a lot of concern about accurate and sensitive detection of imported wild and vaccine derived polioviruses (vdpvs) in polio-free countries, in this study we assessed and compared the sensitivity of t...

Given the actual risk of poliomyelitis outbreaks in region due to poliovirus derived from Sabin vaccine or importation wild poliovirus, Latin American Society Pediatric Infectious Diseases commissioned an ad hoc group experts institution's Vaccines and Biologicals Committee, draft official position paper on urgent need increase immunization levels against disease incorporate inactivated polio e...

The absolute laboratory containment of any virus cannot be guaranteed, but a wealth of experience indicates that effective containment of wild poliovirus materials for global certification is technically and operationally feasible. Effective containment is based on the principles of minimal wild poliovirus infectious and potentially infectious materials in laboratories; minimal risks of operati...

     Poliomyelitis is a highly infectious viral disease which is mainly transmitted via contaminated food and drinking water by human feces, especially in situations of poor hygiene and sanitation (1). This disease is caused by 3 types of wild poliovirus (WPV) (types 1, 2 and 3), and immunity against one type does not create immunity against other types. In our country according National Immuni...

BACKGROUND Sensitive poliovirus surveillance to detect vaccine-derived-polioviruses will continue to increase in importance. OBJECTIVE Isolating and identifying poliovirus strains from children of pediatrics age in Nigeria. METHODS A total of 120 fecal samples were randomly collected from children under the age of five who presented with acute flaccid paralysis. Samples were tested by tissu...

of molecular methods for enterovirus detection, there would be fewer isolates available in future years. To date, nearly 400 poliovirus isolates have been proven to be Sabin vaccine-like. Once the large number of isolates from NSW has been screened, over 950 enteroviruses will have been tested to exclude wild poliovirus. With the expected global eradication of wild poliovirus by the end of the ...

Because circulation of wild poliovirus in the region has been interrupted, the only known sources of wild poliovirus remaining are within the region’s laboratories. These laboratories may store specimens from known poliomyelitis cases or store other materials that are potentially infected with wild poliovirus (Box 1). Therefore, the task of poliomyelitis eradication will not be complete until a...