The wild mint "Mentha longifolia (L.) Hudson subsp. noeana (Briq.) Briq." is an important medicinal plant which contains several worthy components like: menthone, pulegone, pipertenon, menthol, thymol, and carvone in its essential oil. This plant grows extensively in center of Asia including Iran. Because of so worthy components and its big role in traditional and modern medicine, the wild mint...

Mints/X11s are adaptor proteins composed of three isoforms: neuron-specific Mints 1 and 2, and the ubiquitously expressed Mint 3. We have now analyzed constitutive and conditional knock-out mice for all three Mints/X11s. We found that approximately 80% of mice lacking both neuron-specific Mint isoforms (Mints 1 and 2) die at birth, whereas mice lacking any other combination of Mint isoforms sur...

Aberrant amyloid β (Aβ) production plays a causal role in Alzheimer disease pathogenesis. A major cellular pathway for Aβ generation is the activity-dependent endocytosis and proteolytic cleavage of the amyloid precursor protein (APP). However, the molecules controlling activity-dependent APP trafficking in neurons are less defined. Mints are adaptor proteins that directly interact with the end...

OBJECTIVES This in vitro study evaluated the antimicrobial effects of commercial toothpastes containing natural compounds. MATERIALS AND METHODS The study groups were divided based on the natural compound present in the toothpaste composition: Sorbitol (I), tocopherol (II), mint (III), cinnamon/mint (IV), propolis/melaleuca (V), mint/açai (VI), mint/guarana (VII), propolis (VIII), negative co...

Colorectal cancer (CRC) has traditionally been classified into two groups: microsatellite stable/low-level instability (MSS/MSI-L) and high-level MSI (MSI-H) groups on the basis of multiple molecular and clinicopathologic criteria. Using methylated in tumor (MINT) markers 1, 2, 12, and 31, we stratified 77 primary CRCs into three groups: MINT++ (>2), MINT+ (1-2), and MINT- (0 markers methylated...

Mints (also called X11-like proteins) are adaptor proteins composed of divergent N-terminal sequences that bind to synaptic proteins such as CASK (Mint 1 only) and Munc18-1 (Mints 1 and 2) and conserved C-terminal PTB- and PDZ-domains that bind to widely distributed proteins such as APP, presenilins, and Ca(2+) channels (all Mints). We find that Mints 1 and 2 are similarly expressed in most neu...

Respiratory and cutaneous adverse reactions to mint can result from several different mechanisms including IgE-mediated hypersensitivity, delayed-type hypersensitivity (contact dermatitis), and nonimmunologic histamine release. Reactions to cross-reacting plants of the Labiatae family, such as oregano and thyme, as well as to the chemical turpentine, may clue the clinician in on the diagnosis o...

Protein interaction databases represent unique tools to store, in a computer readable form, the protein interaction information disseminated in the scientific literature. Well organized and easily accessible databases permit the easy retrieval and analysis of large interaction data sets. Here we present MINT, a database (http://cbm.bio.uniroma2.it/mint/index.html) designed to store data on func...

The repellency and toxicity of mint oil to American, Periplaneta americana (L.), and German, Blattella germanica (L.), cockroaches were evaluated in a series of laboratory experiments. In topical application experiments, mint oil was toxic to both species with toxicities (LD50s) of 2.57 (1.98– 4.20) in 10 l and 3.83 (2.35–7.34)% in 2 l for American and German cockroaches, respectively. In conti...

This report describes how the Mach 3.0 operating system was ported to the Mobile Internet Router (MINT). The MINT is a router for Mobile IP that is used in the Walkstation project. The report also presents other operating systems that could be suitable for the MINT.