In the present study, methanolic extracts of roots of Vitex negundo L. and extracts of leaves of Vitex negundo L., Ricinus communis L. and Aegle marmelos Corr. were explored for possible antifilarial effect against Brugia malayi microfilariae. It was observed that among the herbal extracts, root extract of Vitex negundo L. and leaves extract of Aegle marmelos Corr. at 100 ng/ml concentration sh...

Maximal electroshock seizures (MES) in albino rats and pentylenetetarazole (PTZ) induced seizures in albino mice were used to study anticonvulsant activity of Vitex-negundo leaf extract. The ethanolic leaf extract of Vitex-negundo was administered orally in graded doses (250, 500 and 1000 mg/kg p.o) in both the experimental models and the effects were compared with diphenylhydantoin in MES meth...

ObjectiveAs the leaves of Vitex negundo L. possess anti-inflammatory and antioxidant properties, this study has been undertaken to evaluate the effect of Vitex negundo L. in experimentally induced inflammatory bowel disease (IBD) and to find its probable mechanism of action including its antioxidant potential. Methods-The extract of Vitex negundo L. was prepared by percolation method. Acute tox...

Resume of 'previous work.?Vaughan (1921) found that an aqueous infusion of the leaves of Vitex peduncularis, Wall, var. roxburghiana, was being used by the aboriginal tribe of Ranchi in malaria and blackwater fever. Though the medicinal properties of the members of the Vitex family (e.g. Vitex trifolia, negundo, etc.) have been elaborately described in the Ayurvedic system of medicine, the Vite...

This study was done to assess the total phenolic compounds (TPC) and 1, 1-diphenyl-2picrylhydrazyl (DPPH) scavenging activity in the flowers and leaves of Clitoria ternatea and Vitex negundo Linn. by using methanol and water extraction. TPC were evaluated using Folin-Ciocalteau method. Methanol was more efficient in extracting phenolic compounds compared with water in measuring TPC. Vitex negun...

Vitex negundo Linn. belong to family Verbenaceae. It is an important medicinal plant. Literature survey of V. negundo revealed the presence of different classes of natural products including essential oil, triterpenes, diterpenes, sesquiterpenes, lignan, flavonoids, flavones glycosides, iridoid glycosides, and stilbene derivative. The plant is traditionally reported for its use for the treatmen...

The in vitro antioxidant potential assay between ethanolic extracts of two species from the genus Vitex (Vitex negundo L. and Vitex trifolia L.) belonging to the Lamiaceae family were evaluated. The antioxidant properties of different extracts prepared from both plant species were evaluated by different methods. DPPH scavenging, nitric oxide scavenging, and β-carotene-linoleic acid and ferrous ...

There is a world wide interest in searching for the safe and effective novel antibacterial compounds of plant origin for the control of plant pathogenic bacteria which is responsible for the great impact on the growth and productivity of agriculture crops. In this study an attempt was made to determine the in vitro antibacterial activity of sequentially extracted different solvent (dichlorometh...

Aims: To evaluate the hepatoprotective activity of Vitex negundo Linn. and Moringa oleifera Lam. In paracetamol induced hepatotoxicity in rats. Materials and Methods: Liver damage was induced in 42 albino rats by paracetamol (1 g/kg P.O.) once daily for a period of 7 days. Silymarin was taken as the standard drug in a dose of 25 mg/kg P.O. Albino Wistar rats (150-200 g) were divided into groups...

Use of repellents seems to be most reliable method of personal protection against annoyance and infections associated with haematophagous insects. We have investigated the biting activity of Simulium and tested the repellency of five essential oils extracted from Homalomena aromatica Schott (Alismatales: Araceae), Pogostemon heyneanus Bentham (Lamiales: Lamiaceae), Citrus aurantifolia Swingle (...