نتایج جستجو برای: Venom protein

تعداد نتایج: 1242407  

ژورنال: کومش 2022

Introduction: Infectious diseases, mainly caused by bacterial agents, are one of the most common causes of death worldwide. A significant number of these agents have been resistant to one or more antibiotics; some of them are multi-drug resistant and others are extensively drug resistant. Various antimicrobial and anticancer compounds have been reported from the venom of various species of scor...

Background and purpose: Vipera lebetina lives in different areas in Iran, and its venom contains a variety of proteins with coagulant and anticoagulant activities. Fibrinolytic enzymes could have a therapeutic role in dissolution of blood clots, so, this study aimed at separating the venom components of Iranian V. lebetina and detecting its anticoagulant activity. Materials and methods: In thi...

Hossein Salmanizadeh Hossein Zolfagharian, Mahdi Babaie

  Objective(s): Echis carinatus is one of the venomous snakes in Iran. The venom of Iranian Echis carinatus is a rich source of protein with various factors affecting the plasma protein and blood coagulation factor. Some of these proteins exhibit types of enzymatic activities. However, other items are proteins with no enzymatic activity.   Materials and Methods: In order to study the mechanism ...

Journal: :iranian journal of basic medical sciences 0
mahdi babaie young researches and elites club, science and research branch, islamic azad university, tehran, iran hossein salmanizadeh young researches and elites club, science and research branch, islamic azad university, tehran, iran hossein zolfagharian department of venomous animals and antivenom production, razi vaccine and serum research institute, karaj, iran

objective(s): echis carinatus is one of the venomous snakes in iran. the venom of iranian echis carinatus is a rich source of protein with various factors affecting the plasma protein and blood coagulation factor. some of these proteins exhibit types of enzymatic activities. however, other items are proteins with no enzymatic activity.   materials and methods: in order to study the mechanism an...

Journal: :journal of arthropod-borne diseases 0
ersenaydın yağmur alaşehir vocational school, celal bayar university, alaşehir, manisa, turkey. özcan özkan drug and medical device agency of turkey, turkey. kzafer karaer department of entomology and protozoology, faculty of veterinary medicine, ankara university, turkey.

background : in this study, we investigated the lethal potency, electrophoretic protein pattern and in vivo effects of hottentotta saulcyi scorpion venom in mice. methods : scorpions were collected at night, by using a uv lamp from mardin province, turkey. venom was obtained from mature h. saulcyi scorpions by electrical stimulation of the telson. the lethality of the venom was determined by i....

Extended Abstract Introduction and Objective: People are sensitive to bee venom and the presence of allergenic compounds in the venom has made it difficult to use and determine the optimal dose for treatment. The aim of this study was to reduce allergenic compounds and to evaluate the quality of gamma ray processed bee venom. Material and Methods: Venom samples were irradiated at dose...

Journal: :Biologics 2022

Venom from different organisms was used in ancient times to treat a wide range of diseases, and combat variety enveloped non-enveloped viruses. The aim this silico research investigate the impact honeybee venom proteins peptides against Ebola virus. In current study, online offline tools were used. RaptorX (protein 3D modeling) PatchDock (protein–protein docking) as tools, while Chimera LigPlot...

ژورنال: کومش 2022

Introduction: The venom of Jellyfish venom contains a variety of bioactive proteins that can be studied for vaccine application. Poly-Lactic Acid is a biodegradable polymer that is used in vaccine systems. The aim of this study was to encapsulate the C-CfTX1-STxB protein into PLA-PEG-PLA three-block copolymer and its immunogenicity study in mice. Materials and Methods: After purification, the p...

Journal: :journal of biotechnology and health sciences 0
ali bazi cancer molecular pathology research center, faculty of medicine, imam reza hospital, mashhad university of medical sciences, mashhad, ir iran; faculty of allied medical sciences, zabol university of medical sciences, zabol, ir iran; faculty of allied medical sciences, zabol university of medical sciences, zabol, ir iran. tel/fax: +98-5432232166 mehran gholamin division of human genetics, immunology research center, avicenna research institute, mashhad university of medical sciences, mashhad, ir iran mohsen sisakht department of biochemistry, faculty of medicine, mashhad university of medical sciences, mashhad, ir iran mohammad reza keramati cancer molecular pathology research center, faculty of medicine, imam reza hospital, mashhad university of medical sciences, mashhad, ir iran

background glioblastoma is a type of brain tumor with poor response to available therapies, and shows high rate of mortality. despite remarkable advancements in our knowledge about cytogenetic and pathophysiologic features of glioblastoma, current treatment strategies are mainly based on cytotoxic drugs; however, these therapeutic approaches are facing progressive failure because of the resista...

Journal: :Ukrainian Biochemical Journal 2023

Because of the catastrophic consequences COVID-19 on world population, there should be novel­ interventions to handle ongoing infections and daily death cases. The aim current study is examine effectiveness HBV (Honeybee venom) proteins spike protein RBD by in silico tools. sequences 5 were used for homology modeling Phyre 2. generated models employed protein-protein docking against Omicron Spi...

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