Although the etiology of varicose veins remains unknown, recent studies have focused on endothelial cell integrity and function because the endothelium regulates vessel tone and synthesizes many pro- and anti-inflammatory factors. The aim of this study was to investigate the evidence involving the endothelium in the development of varicose vein disease. In addition, tissue remodeling was invest...

although the etiology of varicose veins remains unknown, recent studies have focused on endothelial cell integrity and function because the endothelium regulates vessel tone and synthesizes many pro- and anti-inflammatory factors. the aim of this study was to investigate the evidence involving the endothelium in the development of varicose vein disease. in addition, tissue remodeling was invest...

background: proton induced x-ray emission (pixe) has been applied as reliable and improved techniques in this study to compare concentration of various trace elements in normal and abnormal varicose veins. materials and methods: five samples from normal veins and 13 samples from varicose veins bombarded by 2.0 mev energy proton beams produced by a van de graff accelerator in vacuum. two specime...

Objective(s): We intended to determine whether the ovarian varicose which is one of the common etiologies of the pelvic congestion syndrome, has the ability to interfere with the DNA methylation reprogramming in the oocyte and thereby affect the oocyte quality or not. Materials and Methods: Varicose model was induced according to the Turner’s method in the rats. Briefly, a 20-gauge needle was p...

Varicose veins affect approximately one-third of the adult population and result in significant psychological, physical, and financial burden. Nevertheless, the molecular pathogenesis of varicose vein formation remains unidentified. Venous hypertension exerted on veins of the lower extremity is considered the principal factor in varicose vein formation. The role of mechanotransduction of the hi...

INTRODUCTION Red blood cells' (RBC) rheological properties are disturbed in chronic venous disease (CVD). The aim of the study was to compare deformability and aggregation of erythrocytes taken from the varicose vein and the antecubital vein of patients with chronic venous disease. MATERIALS AND METHODS Blood samples were taken from twelve CVD patients presenting clinical, aetiological, anato...

This study was designed to evaluate the role of the smooth muscle cell and the apoptosis in the pathogenesis of the varicose vein. Segments of saphenous vein were obtained from healthy subjects and from those with varicose veins. The vein specimens were subdivided according to subject age (younger or older than 50 years) and according to the varicose vein source (distal or proximal). Morphologi...

background: venous diseases including varicose veins and chronic venous insufficiency are one of the most important pathogenic factors worldwide. high prevalence of varicose veins and its complications is an emerging problem in the twenty-first century. this study aimed to determine the prevalence and associated risk factors of varicose veins in female hairdressers in shahroud, north of iran in...

Overview Varicose veins of the lower extremities are found in the superficial venous system which includes the great saphenous vein (GSV) and the small saphenous vein (SSV), and their tributaries. One-way valves are present in the superficial venous system. These valves prevent backward flow of blood within the vein (reflux) and keep the blood moving toward the heart. The condition of improperl...