Background: Varicella-zoster infection is a serious and potentially fatal disease, especially among newborns.Several studies have described postnatal varicella zoster exposure among neonates and reported on the efficacy of varicella-zoster immunoglobulins (VZIG) used as post-exposure prophylaxis. Unfortunately, VZIG is not available in Jordan. A limited number of studies have investigated the e...

      Varicella is a common and worldwide disease in childhood. It causes primary (chickenpox) and latent infection that may lead to a reactivation disease called zoster (shingles). Zoster or shingles is caused by reactivation of the virus that has been latent in the spinal dorsal ganglion and may occur even in immunocompetent hosts. Although zoster is rare in children, it ma...

This topic will review the pathogenesis, epidemiology, risk factors for, clinical features, diagnosis, and treatment of VZV vasculopathy. The major clinical manifestations and complications of chickenpox and herpes zoster are discussed separately. (See "Epidemiology of varicella-zoster virus infection: Chickenpox" and "Treatment of varicella-zoster virus infection: Chickenpox" and "Vaccination ...

Whether reexposure of varicella-immune persons to varicella-zoster virus would protect against or predispose to development of zoster was analyzed. The rate of zoster in 511 leukemic recipients of varicella vaccine who had 1 or > 1 dose of varicella vaccine and in those who did or did not have a household exposure to varicella was determined. A Kaplan-Meier life-table analysis revealed that the...

Varicella and herpes zoster during pregnancy has been associated with birth defects, neonatal varicella, herpes zoster in newborns and infants. The aim of the present study was to determine the consequences for the neonates, whose mothers were closely exposed to varicella zoster virus (VZV) during pregnancy. Fifty six pregnant women with uncertain histories of prior VZV infection, after a close...

conclusions in this region, a significant proportion of children are susceptible to vzv, severe varicella and it’s complications at older ages. it is recommended for varicella vaccine to be added to routine childhood vaccination programs and also to be injected to susceptible adolescents. negative history of varicella would be a predictor of varicella antibody status in children and young adult...

Healthcare workers are recommended to get vaccinated against measles and varicella. This study aims describe the implementation process of a varicella vaccination program report on reduction in number susceptible healthcare exposed measles, varicella, disseminated herpes zoster at tertiary hospital. The Consolidated Framework for Implementation Research (CFIR) model was used implemented from Oc...

In December 2012, the Food and Drug Administration (FDA) approved VariZIG, a varicella zoster immune globulin preparation (Cangene Corporation, Winnipeg, Canada) for use in the United States for postexposure prophylaxis of varicella for persons at high risk for severe disease who lack evidence of immunity to varicella* and for whom varicella vaccine is contraindicated. Previously available unde...

BACKGROUND The authors sought to monitor the impact of widespread varicella vaccination on the epidemiology of varicella and herpes zoster. While varicella incidence would be expected to decrease, mathematical models predict an initial increase in herpes zoster incidence if re-exposure to varicella protects against reactivation of the varicella zoster virus. METHODS In 1998-2003, as varicella...