Background: Varicella-zoster infection is a serious and potentially fatal disease, especially among newborns.Several studies have described postnatal varicella zoster exposure among neonates and reported on the efficacy of varicella-zoster immunoglobulins (VZIG) used as post-exposure prophylaxis. Unfortunately, VZIG is not available in Jordan. A limited number of studies have investigated the e...

      Varicella is a common and worldwide disease in childhood. It causes primary (chickenpox) and latent infection that may lead to a reactivation disease called zoster (shingles). Zoster or shingles is caused by reactivation of the virus that has been latent in the spinal dorsal ganglion and may occur even in immunocompetent hosts. Although zoster is rare in children, it ma...

This topic will review the pathogenesis, epidemiology, risk factors for, clinical features, diagnosis, and treatment of VZV vasculopathy. The major clinical manifestations and complications of chickenpox and herpes zoster are discussed separately. (See "Epidemiology of varicella-zoster virus infection: Chickenpox" and "Treatment of varicella-zoster virus infection: Chickenpox" and "Vaccination ...

varicella zoster virus (vzv), the causative agent of chicken pox and shingles, can cause severe systemic infections of the cns and the respiratory tract in immunocompetent individuals as well as in immunocompromized patients. the aim of this cross-sectional study was to assess the prevalence of antibody varicella zoster virus in different age groups. the enzyme linked immunosorbent assay (elisa...

The varicella zoster virus primarily causes chickenpox. Herpes zoster is a typical late manifestation with reactivation of latent virus in sensory ganglia. Chickenpox is a highly contagious disease. Herpes zoster has been assumed to be less contagious, but studies have shown that reactivation of the varicella zoster virus also leads to significant spread of the virus (1–4). There has been incre...

In December 2012, the Food and Drug Administration (FDA) approved VariZIG, a varicella zoster immune globulin preparation (Cangene Corporation, Winnipeg, Canada) for use in the United States for postexposure prophylaxis of varicella for persons at high risk for severe disease who lack evidence of immunity to varicella* and for whom varicella vaccine is contraindicated. Previously available unde...

background and objectives: varicella zoster virus (vzv) infection in pregnant women can cause complications for the mother and fetus. the aim of this study was to assess the immunity against vzv among young women before marriage. materials and methods: in this cross-sectional study 250 of women referring to health centers in sanandaj, iran, for pre-marital medical check-up were selected. the vz...

varicella zoster virus (vzv) is a member of herpes family viruses, which causes varicella (chickenpox) after primary infection and herpes zoster (shingles) because of latent virus reactivation from dorsal root ganglia. generally, prevalence of varicella antibodies increases with age. we aimed to compare the prevalence of anti-vzv antibody in children under seven years old, in order to obtain a ...

Varicella zoster virus fetopathy occurs in infants after infection with varicella-zoster virus from mother during the fi rst two trimesters of pregnancy. The authors describe the case of a female infant, aged 4 months, which came under observation for neuro developmental delay for chronological age. Neurological exam, abnomalities detected on ophthalmologic examination, maternal history of gest...