In this study the restriction endonuclease analysis (REA) technique was used for the comparison of field isolates and vaccinal strain of Pasteurella multocida using Hha-I enzyme. On the basis of DNA finger prints, extent of homology among the field isolates and the vaccinal strain was observed. The study has provided the clear evidence that eight isolates of P. multocida used were serologically...

Bacillus anthracis strain SPV842_15 was isolated from bovine fetus, while B. anthracis strain Brazilian vaccinal was recovered from a commercial vaccine. We report here the genome sequences of both strains. The SPV842_15 genome is composed of a single circular chromosome with a length of 5,228,664 base pairs, and comprises 5911 coding sequences. In turn, the Brazilian vaccinal genome remains in...

Avian infectious bronchitis is an acute and highly contagious disease that mainly causes respiratory symptoms in poultry. A number of serotypes and variants of the viral agent with poor cross-protection are the major problem to achieve desired immunity from vaccination. The S1 subunit of S glycoprotein (spike) is the major determinant of IBV so that a minor change in amino acid sequence of this...

avian infectious bronchitis is an acute and highly contagious disease that mainly causes respiratory symptoms in poultry. a number of serotypes and variants of the viral agent with poor cross-protection are the major problem to achieve desired immunity from vaccination. the s1 subunit of s glycoprotein (spike) is the major determinant of ibv so that a minor change in amino acid sequence of this...

This review presents many of numerous studies realized in the past century by Romanian researchers who contributed directly or indirectly to progress in animal anthrax specific prevention and imunological diagnosis of the disease. It is underlined Nicolae Stamatin’s great contribution; he obtained a new acapsulated and attenuated vaccinal strain of B. anthracis whose mass use led to a dramatica...

In order to show the type and severity of gross and histopathologic lesions induce by vaccinal strain (serotype A1) of Pateurella mulocida, ten four-week-old SPF chickens were inoculated intramuscularly with 75 cfu of ( 0.5 ml of 10-7 dilution) bacterium. All birds died in less than 16 hours. No prominent gross lesions were observed in different organs. In microscopic examination, the most comm...

In Ethiopia, immunization of cattle against contagious bovine pleuropneumonia (CBPP) has been practiced for the last 4 decades using vaccines prepared from streptomycin-resistant vaccine seed strain. Recently, a vaccine strain denominated T1/44 has been introduced to Ethiopia to prepare vaccine for filed use. A total of 296,248 cattle were vaccinated with vaccine produced from this seed strain ...

The gram-negative bacteria Brucella melitensis was investigated to evaluate its susceptibility to UVC radiation at 254 nm. At an intensity of 18.7 mW/cm2 of UVC, the time required for inactivation of B. melitensis was 240 seconds in both dark and light, whereas it was 120 seconds and 240 seconds in dark and light respectively at an intensity of 19.5 mW/cm2. The results indicate that vaccinal st...

The use of peptide immuno-modulating agents for vaccinal prevention in population does not have practical application for a number of reasons. At the first place it is related to the fact that occurence of postprimary immunodeficient condition in subjects who must be vaccinated normally does not lead to significant decrease of spesific immune response and is not considered to be contradiction t...