Background: Uterine factor infertility (UFI) refers to the refractory causes of female infertility stemming from the anatomical or physiological inability of a uterus to sustain gestation. Today, uterine factor infertility affects 3-5% of the population. Traditionally, although surrogacy and adoption have been the only viable options for females affected by this condition, the uterine transplan...

Uterine transplantation is an evolving procedure to allow for childbearing in paitents with absolute uterine factor infertility. The objective of this study was review the existing literature using a comprehensive PubMed search. A systematic medical subheadings search strategy used terms “uterus transplant” and “uterine transplantation”. Of 75 full-text articles assessed eligibility, 68 were in...

A uterine transplant, or womb provides a potential treatment for women who cannot become pregnant carry pregnancy because they do not have womb, that is unable to maintain pregnancy. This estimated affect one in 500 women. Options those wish start family include adoption and surrogacy, but these are associated with legal, cultural, ethical religious implications may be appropriate some their fa...

Up to 15% of the reproductive population is infertile, and 3 to 5% of these cases are caused by uterine dysfunction. This abnormality generally leads women to consider surrogacy or adoption. Uterine transplantation, although still experimental, may be an option in these cases. This systematic review will outline the recommendations, surgical aspects, immunosuppressive drugs and reproductive asp...

Although a close connection between uterine regeneration and successful pregnancy in both humans and mice has been consistently observed, its molecular basis remains unclear. We here established a mouse model of decellularized uterine matrix (DUM) transplantation. Resected mouse uteri were processed with SDS to make DUMs without any intact cells. DUMs were transplanted into the mouse uteri with...

For women with absolute uterine factor infertility (AUFI), uterus transplantation (UTx) is now an alternative to gestational surrogacy or adoption in order have a child [...]

A 47-year-old woman underwent living renal transplantation at the age of 41 and had been taking oral immunosuppressive drugs. She was diagnosed with intramural myoma suspected lobular endocervical glandular hyperplasia. Laparoscopic modified radical hysterectomy planned. Before operation, everolimus changed to mycophenolate mofetil because wound healing complications. Location transplanted pelv...

Most women with uterine factor infertility have today no prospect of carrying a pregnancy to term. The development of a method for transplantation of the human uterus would be a means for many of these women to become both genetic and gestational mothers. In this article we review the literature concerning the history and recent development in the area of uterine transplantation. We describe ou...

Important developments in transplantation recent years have brought uterine to the agenda. Transplantation has been a glimmer of hope for many patients with factor infertility. Most women only want child they gave birth to. However, most important feature that distinguishes uterus from other surgeries is it performed not save people's lives, but increase quality life. This situation raises ques...

Minimally invasive surgery, specifically robotic surgery, became a common technique used by gynecological surgeons over the last decade. The realization of the first human uterine transplantation commenced new perspectives in the treatment of uterine agenesia or infertility in women with history of hysterectomy at a young age. Robot-assisted technique may enhance the safety of the procedure by ...