objective: helicobacter pylori (h. pylori) is the most common pathogenic bacteria in the stomach. the aim of the current study was to explore the effect of oral garlic administration on bacterial urease activity inside the stomach and its contribution to the treatment of h. pylori infection.   materials and methods: in this clinical trial, 15 patients were studied quantitatively with urease bre...

helicobacter pylori infection is one of the most common human infections which have been associated with many upper gasterointestinal complications. different treatment regimens for helicobacter pylori eradication have been used. one of these regimes is the quadruple therapy regimen which metronidazole is one of the medications. in recent years several reports on h. pylori resistance to this an...

BACKGROUND Accuracy of the most frequently used tests for diagnosing Helicobacter pylori infection in patients with upper gastrointestinal bleeding of peptic origin is determined. METHODS Seventy-eight patients with endoscopically-proven upper gastrointestinal bleeding of peptic origin were included. The presence of H. pylori was considered when observed from the histology or, if negative, wh...

Helicobacter pylori is a human pathogen that infects over 50% of the population worldwide. It is the most important etiologic agent of gastroduodenal ulcers and malignancies. Helicobacter pylori urease enzyme is considered the main factor for the organism's colonization in the gastroduodenal mucosa. Hens immunized with the purified urease produce a highly specific anti-H. pylori urease immunogl...

BACKGROUND/AIMS The influence of different media on the validity of the rapid urease test, including accuracy, reaction time and cost-effectiveness is evaluated. METHODOLOGY Biopsies were obtained from the antral and body mucosa of 100 KMUH patients (51 men, 49 women; mean age: 54.0 years, range: 21-79 years old) undergoing gastroendoscopy due to dyspepsia. None of the patients had received a...

CONTEXT Multiple diagnostic methods are available for the detection of Helicobacter pylori infection, but at present no single one can be used as the gold standard. OBJECTIVE The aim of this study was to evaluate the diagnostic accuracy of 3 invasive and 2 non-invasive methods for detection of Helicobacter pylori infection in symptomatic children and adolescents. DESIGN Prospective cohort s...

Helicobacter pylori infection is supposed to be one of the major causes of digestive and other diseases. Among a lot of invasive and non-invasive methods for its detection, none is ideal. The aim is an assessment of the Helicobacter pylori infection in the stomach using breath test and comparison to other diagnostic methods, as well as following up the effects of therapy. In 17 patients with di...

INTRODUCTION The endoscopic diagnosis of Helicobacter pylori infection in patients with bleeding peptic ulcer is limited by a decreased sensitivity in standard invasive tests, rapid urease test and histology. There is controversy about the convenience of using one, neither, or both diagnostic tests. AIMS To evaluate the results of simultaneously performed rapid urease test and histology in th...

Background: Acid test meals may improve the accuracy of the C urea breath test (UBT). This has been attributed to changes in gastric emptying rather than to the effects of gastric pH on Helicobacter pylori urease. Aims: To determine whether enhancement of CO2 excretion in the UBT in H pylori infected volunteers by acidification of a test meal is due to a delay in gastric emptying. Methods: Urea...

OBJECTIVE To assess the accuracy of the determination of Helicobacter pylori infection by a stool immunoassay in patients with upper-gastrointestinal bleeding (UGB) of peptic origin, in comparison with the routine histological study, serology, rapid urease and 13C-breath tests. METHODS Sixty-eight patients with endoscopically proven UGB of peptic origin were included. The presence of H. pylor...