نتایج جستجو برای: Tumoral-MSCs
تعداد نتایج: 13293 فیلتر نتایج به سال:
background: differentiation, migratory properties and availability of mesenchymal stromal cells (msc) have become an important part of biomedical research. however, the functional heterogeneity of cells derived from different tissues has hampered providing definitive phenotypic markers for these cells. objective: to characterize and compare the phenotype and cytokines of adipose derived mscs (a...
Background: Differentiation, migratory properties and availability of Mesenchymal Stromal Cells (MSC) have become an important part of biomedical research. However, the functional heterogeneity of cells derived from different tissues has hampered providing definitive phenotypic markers for these cells. Objective: To characterize and compare the phenotype and cytokines of adipose derived MSCs (...
Glioblastoma (GBM) is one of the most malignant and devastating brain tumors. The presence highly therapy-resistant GBM cell subpopulations within tumor mass, rapid invasion into tissues reciprocal interactions with stromal cells in microenvironment contributes to an inevitable fatal prognosis for patients. We highlight recent evidence crosstalk mesenchymal stem (MSCs), which occurs either by d...
Human mesenchymal stem cells (MSCs) represent a novel carrier for gene therapy and apoptin is a potential tumor-selective apoptosis-inducing protein. In the present study, the anti-tumoral effect of MSCs modified with apoptin against lung carcinoma was evaluated. Apoptin protein was expressed in a prokaryotic expression system and purified by affinity chromatography. Subsequently, anti-apoptin ...
Adoptively transferred mesenchymal stem cells (MSCs) home to solid tumors. Biologic features within the tumor environment can be used to selectively activate transgenes in engineered MSCs after tumor invasion. One of the characteristic features of solid tumors is hypoxia. We evaluated a hypoxia-based imaging and therapy strategy to target expression of the sodium iodide symporter (NIS) gene to ...
Background Since cartilage, unlike skin, does not contain vessels, it obtains nutrition by diffusion. This reduces graft viability, resulting in problems such as reductions size, changes shape, and resorption of the cartilage late post-graft period. study aimed to investigate effects adipose-derived mesenchymal cells conditioned medium (CM) on viability.Methods Dissections were performed 4 mont...
The immune responses of humans and animals to insults (i.e., infections, traumas, tumoral transformation and radiation) are based on an intricate network of cells and chemical messengers. Abnormally high inflammation immediately after insult or abnormally prolonged pro-inflammatory stimuli bringing about chronic inflammation can lead to life-threatening or severely debilitating diseases. Mesenc...
In this article, the CT, three-dimensional CT, and MR findings are reviewed in a 59-year-old woman with tumoral calcinosis involving the temporomandibular joint.
خون بند ناف (ucb) به عنوان یک منبع از سلول های بنیادی خون ساز (hsc) در درمان بیماری های خونی استفاده می شود. به دلیل ناکافی بودن تعداد سلول های cd34+ خون بند ناف و کاربرد این منبع سلولی در پزشکی، تکثیر این سلول ها در دارای اهمیت می باشد. سلول های استرومائی مزانشیمی (mscs) در حفظ و نگهداری hscs نقش مهمی داشته و به عنوان لایه تغذیه کننده در تکثیر hscs جدا شده از خون بند ناف مورد استفاده قرار می گ...
مقدمه: خون بندناف (ucb) به عنوان یک منبع از سلولهای بنیادی خونساز (hsc) است.این سلول ها نیای سلولهایی است که می توانند سیستم خونساز در بیماران مبتلا به بیماریهای بد خیم و خوش خیم را بازسازی کنند.سلولهای بنیادی مزانشیمی (mscs) که از خون بند ناف انسان (hucb) مشتق می شوند ، در محیط آزمایشگاه،به انواع مختلفی از سلولها از جمله استخوان،غضروف وچربی تمایز یافته اند.این مطالعه،امکان تبدیل سلولهای بنیاد...
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