نتایج جستجو برای: Tropicamide, Validation

تعداد نتایج: 174476  

Journal: :iranian journal of pharmaceutical sciences 0
souri effat department of medicinal chemistry, faculty of pharmacy and pharmaceutical research center, tehran university of medical sciences, tehran (14155-6451), iran massoud amanlou department of medicinal chemistry, faculty of pharmacy and pharmaceutical research center, tehran university of medical sciences, tehran (14155-6451), iran shiva shahbazi department of medicinal chemistry, faculty of pharmacy and pharmaceutical research center, tehran university of medical sciences, tehran (14155-6451), iran mitra bayat department of medicinal chemistry, faculty of pharmacy and pharmaceutical research center, tehran university of medical sciences, tehran (14155-6451), iran

tropicamide is an antimuscarinic agent used as eye drops for refractive examinations. the aim of this study was to develop a simple and suitable analytical method for determination of tropicamide in eye drops in the presence of excipients. a zero-crossing third and fourth derivative spectrophotometric method was described for determination of tropicamide in eye drops. the measurements were carr...

Effat Souri, Hassan Farsam Massoud Amanlou, Shiva Izady

     A simple and sensitive extractive spectrophotometric method is described for determination of tropicamide. The method is based on the reaction of tropicamide and bromocresol green. The ion-paired colored complex was extracted with chloroform at pH 3. The extracted complex showed maximum absorbance at 423 nm. The complex was stable up to 2 days and obeyed Beer's law over the concentration r...

Journal: :Journal of pediatric ophthalmology and strabismus 1992
B Bolt B Benz F Koerner E Bossi

Eye drops used for diagnostic mydriasis may produce systemic side effects in preterm infants. Studies on the pupil dilating and systemic effect of various mydriatic agents yielded conflicting results. We conducted a prospective randomized double-blind study on the systemic effect of two mydriatic eye-drop combinations. Thirty-nine preterm infants were randomly assigned to two groups. An eye-dro...

Massoud Amanlou, Mitra Bayat Shiva Shahbazi Souri Effat,

      Tropicamide is an antimuscarinic agent used as eye drops for refractive examinations. The aim of this study was to develop a simple and suitable analytical method for determination of tropicamide in eye drops in the presence of excipients. A zero-crossing third and fourth derivative spectrophotometric method was described for determination of tropicamide in eye drops. The measurements wer...

Journal: :General hospital psychiatry 2013
Francesco Saverio Bersani Ornella Corazza Pierluigi Simonato Anna Mylokosta Ermelinda Levari Raffaele Lovaste Fabrizio Schifano

BACKGROUND Tropicamide is an antimuscarinic drug usually prescribed as an ophthalmic solution to induce short-term mydriasis and cycloplegia. Over the last 2 years, tropicamide has been reported in both Russia and Italy to be self-administered intravenously (IV) for recreational purposes. METHODS The literature on tropicamide was searched in PsycInfo and Pubmed databases. Considering the abse...

2001
Atsuhiko Iijima Munetaka Haida Norio Ishikawa Haruyuki Minamitani Yukito Shinohara

Pupillary response test using a cholinergic antagonist, tropicamide was focused as a diagnostic method of Alzheimer’s disease (AD). Ever since the test was reported, there have been studies that non-AD individuals showed same responses to tropicamide compared to AD individuals and that the test could not be useful for the diagnosis of AD. In this study, we changed the experimental conditions es...

Journal: :iranian journal of pharmaceutical sciences 0
massoud amanlou department of medicinal chemistry, faculty of pharmacy, and pharmaceutical sciences research center, tehran university of medical sciences, tehran, iran effat souri department of medicinal chemistry, faculty of pharmacy, and pharmaceutical sciences research center, tehran university of medical sciences, tehran, iran shiva izady department of medicinal chemistry, faculty of pharmacy, and pharmaceutical sciences research center, tehran university of medical sciences, tehran, iran hassan farsam department of medicinal chemistry, faculty of pharmacy, and pharmaceutical sciences research center, tehran university of medical sciences, tehran, iran

a simple and sensitive extractive spectrophotometric method is described for determination of tropicamide. the method is based on the reaction of tropicamide and bromocresol green. the ion-paired colored complex was extracted with chloroform at ph 3. the extracted complex showed maximum absorbance at 423 nm. the complex was stable up to 2 days and obeyed beer's law over the concentration r...

2017
Jingyi Cheng Jian Yu Chunhui Jiang Xinghuai Sun

Purpose: To evaluate and compare the effect of topical mydriatic eye drops (0.5% tropicamide alone, and a 0.5% tropicamide/0.5% phenylephrine mixture) on the retinal perfusion using optic coherence tomography angiography (OCTA). Methods: The perfused vessel density in the macular and peripapillary areas of both eyes was measured in eight healthy subjects using OCTA and a split-spectrum amplitud...

Journal: :Human psychopharmacology 2015
Francesco Saverio Bersani Claudio Imperatori Mariya Prilutskaya Ramiz Kuliev Ornella Corazza

OBJECTIVES The intravenous (IV) injection of tropicamide for non-clinical purposes is a new and widespread drug trend. The aim of this study is to provide the first literature review on the topic. METHODS Relevant literature was identified through a search of MEDLINE, Psycinfo, Google Scholar, conference proceedings and select citations. RESULTS Cases of tropicamide (IV) injection have been...

2009
Ji-Hyun Park Young-Chun Lee Se-Youp Lee

PURPOSE To maximize effective use of mydriatic drugs through comparing the pupillary dilation effects between 1% tropicamide and 2.5% phenylephrine. METHODS Fifty people requiring pupillary dilation were divided into 3 groups. Group 1 was treated with one drop of 1% tropicamide in the right eye and one drop of 2.5% phenylephrine in the left eye. Group 2 was treated twice during a 5-minute int...

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