The interaction of flavinium salts with triphenylphosphine is described. The complexes which can be isolated in high yields in the crystalline state contain one mole triphenylphosphine per mole flavin. Triphenylphosphine is covalently bound to the N (5)-atom of the isoalloxazine ring system. Dissociation constants and rate constants have been determined spectrophotometrically. Evidence for the ...

Configurationally stable, propeller-like triarylphosphine and triarylphosphine oxide can be synthesized; a chiral scaffold based on Lissoclinum-cyclopeptides linked via three peptide bonds with a triphenylphosphine and triphenylphosphine oxide moiety, respectively, prevents effectively epimerization at the chiral phosphorus atom.

Unactivated carboxylic acids and amines undergo organocatalytic Ph3P/CCl4-mediated amide bond formation by employing in situ reduction of triphenylphosphine oxide to triphenylphosphine in the presence of diethoxymethylsilane and bis(4-nitrophenyl)phosphate.

Heterogeneous polymer-supported triphenylphosphine oxides based on the rasta resin architecture have been synthesized, and applied as reagent precursors in a wide range of halogenation reactions. The rasta resin-triphenylphosphine oxides were reacted with either oxalyl chloride or oxalyl bromide to form the corresponding halophosphonium salts, and these in turn were reacted with alcohols, aldeh...

Reaction of chiral ester linked diynes with chlorotris(triphenylphosphine)cobalt(I) and sodium cyclopentadienide gave (η(5)-cyclopentadienyl)(triphenylphosphine) cobaltacyclopentadiene complexes as single chiral-at-metal diastereoisomers, including a non-racemic example synthesised in three steps from (S)-3-butyn-2-ol.

Crystal structure of trans-dibromobis(triphenylphosphine)platinum(II) was determined by X-ray-crystallography. The complex crystallizes on an inversion center in distorted square planar coordination around platinum with triphenylphosphine ligands in trans positions to each other and with two molecules of dichloromethane as solvate.

A concise (5 to 6 steps), stereodivergent, highly diastereoselective (dr up to >19:1 for both stereoisomers) and scalable synthesis (up to 14 g) of cis- and trans-2-substituted 3-piperidinols, a core motif in numerous bioactive compounds, is presented. This sequence allowed an efficient synthesis of the NK-1 inhibitor L-733,060 in 8 steps. Additionally, a cyclodehydration-realizing simple triet...

In the crystal of the title compound, C(18)H(15)OP·0.5H(2)O, a water molecule links to two adjacent triphenylphosphine molecules by way of O-H⋯O hydrogen bonds. The crystal is twinned, the minor twin component being 36%.

from Wittig-type reactions is a quite useful tool in synthetic organic chemistry, provided that an olefinic product is easily isolable.1 During our exploration of coupling reactions between phthalimide and phosphorane to prepare bioactive phthalimidine derivatives, the inevitably-formed triphenylphosphine oxide was found to mingle with the expected product, making the isolation difficult. Recen...

Di-chloro-bis[chloro(triphenylphosphine)mercury(II)], [Hg2Cl4(C18H15P)2], (I), and di-bromo-bis[bromo(triphenylphosphine)mercury(II)], [Hg2Br4(C18H15P)2], (II), have been reinvestigated at 120 K. The molecules of (I) lie across inversion centres in space group P21/n, and in both (I) and (II) the complexes are linked into three-dimensional frameworks by a combination of CÐH X (X = Cl and Br) and...