Methemoglobin is a structurally modified form of hemoglobin incapable binding oxygen, and elevated levels methemoglobin cause tissue hypoxia. Occupational exposure to 2,4,6-trinitrotoluene, commonly called trinitrotoluene, causes methemoglobinemia. This case report describes 27-year-old male sergeant who developed methemoglobinemia upon trinitrotoluene after blast injury while welding the walls...

Environmental contamination by trinitrotoluene is of global concern due to its widespread use in military ordnance and commercial explosives. Despite known long-term persistence in groundwater and soil, the toxicological profile of trinitrotoluene and other explosive wastes have not been systematically measured using in vivo biological assays. Zebrafish embryos are ideal model vertebrates for h...

Specific nucleic acid aptamers using the microtiter plate based modified SELEX method against explosive trinitrotoluene are reported. Efficient partitioning of dsDNA was carried out using streptavidin labeled gold nanoprobes for the selection of specific aptamers. The selected binders having an affinity of ~10(-7) M were used in the newly developed electrochemical aptasensor, exhibiting a detec...

A rapid spectrophotometric determination for 2,4,6-trinitrotoluene (TNT) is significant because this method is suitable for simultaneous analyses of the numerous samples. We found one problem that TNT reduction products interfere with the TNT detection in this assay, and we overcame this problem by heating the samples at 95 degrees C, resulting in the production of compounds that did not interf...

How can technological thinking be taught without using technology? We ask this question because of the potential offered by myriad good answers. Most importantly, if significant aspects of technological thinking can be taught without direct recourse to technology, the options for reinforcing such thinking throughout a curriculum can be greatly increased. In fact, simply having a clear idea of w...

background: trinitrotoluene (tnt) is one of the most well-known and oldest explosive agents. in the recent decade, bioenvironmental, biochemical, and biological effects of tnt exposure have been more in the spotlight. in this study, we aimed to evaluate spirometric parameters in workers of a tnt factory exposed to tnt and other related fumes and dusts compared with the unexposed controls. metho...

Synthesis of four trinitrotoluene stilbene derivatives and assessment for SERRS activity is reported.