نتایج جستجو برای: Tongue SCC

تعداد نتایج: 30490  

Journal: :iranian journal of otorhinolaryngology 0
reza kaboodkhani department of otorhinolaryngology and head and neck surgery, shiraz university of medical sciences, shiraz, iran. ebrahim karimi otorhinolaryngology research center, tehran university of medical siences, tehran, iran. mohammad taghi khorsandi ashtiani otorhinolaryngology research center, tehran university of medical siences, tehran, iran. safoura kowkabi neurologist, shiraz university of medical sciences, shiraz, iran. mohammad reza firouzifar department of otorhinolaryngology, amir alam hospital, tehran university of medical siences, tehran, iran. farzad yazdani department of pathology, amir alam hospital, tehran university of medical siences, tehran, iran

introduction: 90% of the tumors in the head and neck are squamous-cell carcinomas (hnscc), which have overall 5- year survival rate between 50% -60%. cd44 has been shown to be associated with the prognosis.  materials and methods: biopsy specimens of 51 patients with oral tongue scc were evaluated by immunohistochemistry (ihc) for the cd44 antibody.  results: there was no significant correlatio...

2009
Thian-Sze Wong Wai-Kuen Ho Jimmy Yu-Wai Chan Raymond Wai-Man Ng William Ignace Wei

Human microRNA 184 (miR-184) is overexpressed in squamous cell carcinoma (SCC) of the tongue. In vitro inhibition of miR-184 levels could induce apoptosis and hinder proliferation of tongue SCC cells. Patients with tongue SCC have high plasma miR-184 levels. Plasma miR-184 is likely associated with the tumor load. Surgical removal of the primary tumor reduced plasma miR-184 levels significantly...

2014
Wei Gao Jimmy Yu-Wai Chan Thian-Sze Wong

BACKGROUND The deregulated tumorigenic long non-coding RNA (lncRNA) has been reported in several malignancies. However, there is still no comprehensive study on tongue squamous cell carcinoma (SCC). METHODS Functional reannotation for the human lncRNA was carried out by ncFANs. Real-time quantitative PCR was used to validate the identified lncRNAs. RESULTS Using the functional annotation al...

Journal: :Head & neck 2017
Jia Hui Ng N Gopalakrishna Iyer Min-Han Tan Gustaf Edgren

BACKGROUND There are reports about the changing epidemiology of tongue squamous cell carcinoma (SCC), with recent reports indicating an increasing incidence in young women. METHODS Data on incident cases of tongue SCC were collected from cancer registries worldwide. RESULTS Data from a total of 22 cancer registries and 89,212 incident cases of tongue SCC worldwide were included. Most areas ...

2015
Huan Fan Ki-Yong Yoon Soung-Min Kim Hoon Myoung Jong-Ho Lee Myung-Jin Kim

PURPOSE Squamous cell carcinoma (SCC) of the tongue has a relatively high incidence of all oral cancers. Some studies have reported a relationship between intraoral dental prosthesis and SCC of the tongue; however, this relationship remains controversial. The purpose of this study was to investigate the relationship between SCC of the tongue and the positional aspects of dental prosthesis using...

Journal: :acta medica iranica 0
fatholah behnoud department of ent, besat hospital, school of medicine, hamedan university of medical sciences, hamedan, iran. saadat torabian department of ent, besat hospital, school of medicine, hamedan university of medical sciences, hamedan, iran. maasoumeh zargaran faculty of dentistry, hamedan university of medical sciences, hamedan, iran.

previous studies on etiology of squamous cell carcinoma (scc) of the tongue have reported results with respect to long term exposure to cigarette smoking and alcohol abuse. the aim of this study was to investigate risk factors for scc of the tongue in a set of patients with minimum exposure to cigarette smoking and alcohol. sixty four cases with diagnosis of oral tongue scc were reviewed in thi...

Journal: :Medicina oral, patologia oral y cirugia bucal 2011
Nooshin Mohtasham Shahab Babakoohi Laleh Montaser-Kouhsari Bahram Memar Jahanshah Salehinejad Amin Rahpeyma Saeedeh Khageh-Ahmady Parviz Marouzi Alireza Firooz Hamidreza Pazoki-Toroudi Kazem Anvari

INTRODUCTION In oral cavity, the tongue is the most common site prone to development of squamous cell carcinoma (SCC). Considering malignant transformation as a cellular stress, the expression of heat shock proteins (HSPs) may be affected in this process. In this study we assessed the expression of HSP105 and HSP27 as two of the most interested stress proteins and investigated their relationshi...

2017
Shinsuke Suzuki Kohei Honda Hiroshi Nanjo Nobuko Iikawa Tadahiro Tsuji Yohei Kawasaki Kazuharu Yamazaki Teruyuki Sato Hidekazu Saito Kazuhiro Shiina Kazuo Ishikawa

Cervical lymph node metastasis causes a poor prognosis in cases of stage T1-T2 squamous cell carcinoma (SCC) of the tongue. Recent studies have reported that cluster of differentiation (CD)147, also known as extracellular matrix metalloproteinase inducer, contributes to tumor progression. The present study evaluated the role of CD147 in the tumorigenesis of SCC of the tongue in vitro, as well a...

Introduction: The clinical outcome of patients with squamous cell carcinoma (SCC) located in the head and neck has remained poor despite ongoing advances in diagnosis and management. Interleukin-6(IL-6) is a multi-functional cytokine that plays an important role in the process of cell differentiation and is increased in several malignancies. The aim of this study was to investigate the serum le...

Journal: :Cancer 2005
Caroline H Shiboski Brian L Schmidt Richard C K Jordan

BACKGROUND An increasing incidence of oral carcinoma among young adults has been reported in the U.S. and Europe. Although the association between human papillomavirus infection and tonsillar carcinoma is now well established, to the authors' knowledge little is known about incidence trends in tonsillar carcinoma among younger adults. The objective of the current study was to explore the trends...

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