results migration of cells started on the fifth day. as a result of this migration, most cells were located on the surface of the scaffold and formed epiderm-like structure and some penetrated into the scaffold. by day 25, cells which had penetrated into the scaffold had various destinies such as becoming elongated spindle-shaped cells and creating blood vessel-like structures. conclusions adm ...

objective (s): the scarcity of articular cartilage defect to repair due to absence of blood vessels and tissue engineering is one of the promising approaches for cartilage regeneration. the objective of this study was to prepare an extracellular matrix derived decellularized bovine articular cartilage scaffold and investigate its interactions with seeded rat bone marrow mesenchymal stem cells (...

objective: diabetes plays an important role in the progression of tissue damage. influencing factors of the cellular matrix can lead to changes in the structure and function of tissues or their failure. herbal consumption can be effective in reducing tissue failure. the aim of the this study is to research the effect portulaca oleracea seeds on the levels of matrix metalloproteinase 2, 9 and ti...

statement of problem: various surgical procedures have been used to achieve root coverage and subepithelial connective tissue graft (sctg) is identified as one of the most successful techniques. recently, acellular dermal matrix allograft (adma) has been developed as a substitute for sctg to avoid removing the palatal connective tissue. purpose: the present study compared the clinical efficienc...

breast cancer  patients  are  susceptible to  infections such  as  candidiasis. due  to  the importance and the role of matrix metalloproteinases (mmp) in breast cancer progression and its correlation with tumor metastasis, we analyzed the serum level of mmps -2, -3, -9 and tissue inhibitor of matrix metalloproteinase-1 (timp-1) in breast cancer bearing mice in the presence of systemic candida ...

objective: the aim of this study was to compare subepithelial connective tissue grafts (sctg) and coronally advanced flaps (caf) with the addition of emdogain in the treatment of gingival recession. materials and methods : this interventional randomized controlled clinical trial involved eleven patients and 31 teeth demonstrating facial recessions of > 2 mm identified as miller's class i or ii....

objective: development of high producing mammalian cell lines is a major bottleneck in manufacturing of recombinant therapeutic proteins. this study examines the effect of using the matrix attachment region from the human interferon beta gene in combination with promoter activation strategy with e1a 13s protein on human tissue plasminogen activator (t-pa) expression in chinese hamster ovary (ch...

background: breast cancer is one of the most common cancers in the world, particularly in iran. there are many genomic and molecular factors that cause the occurrence of breast cancer. many markers are associated with tumor invasiveness. matrix metalloproteinase includes a family of zinc-dependent endopeptidases that degrade various components of the extracellular matrix and basement membrane. ...

the high blood rate that often occurs in arteries may play a role in artery failure and tortuosity which leads to blackouts, transitory ischemic attacks and other diseases. however, vibration and instability analysis of carotid arteries are lacking. the objective of this study is to investigate the vibration and instability of the carotid arteries conveying blood under axial tension with surrou...

background: the aim of this clinical trial study was to clinically evaluate the use of enamel matrix protein derivative combined with the coronally positioned fl ap to treat gingival recession compared to the subepithelial connective tissue graft by a new method to obtain denuded root surface area. materials and methods: thirteen patients, each with two or more similar bilateral miller class i ...