نتایج جستجو برای: Timolol maleate

تعداد نتایج: 4125  

2005

Timolol maleate has a molecular weight of 432.50. It is a white, odorless, crystalline powder which is soluble in water, methanol, and alcohol. Timolol maleate is stable at room temperature. Timolol maleate ophthalmic solution is supplied in two formulations: Ophthalmic Solution TIMOPTIC* (timolol maleate ophthalmic solution), which contains the preservative benzalkonium chloride; and Ophthalmi...

2013
William C Stewart Jeffrey C Oehler Neil T Choplin Joseph I Markoff Marlene R Moster Parul Ichhpujani Lindsay A Nelson

OBJECTIVE To evaluate by survey the comfort upon instillation of timolol hemihydrate compared to timolol maleate with potassium sorbate. DESIGN A prospective, multicenter, observational, non-interventional study. PARTICIPANTS One hundred and three patients of open-angle glaucoma or ocular hypertension who were ≥21 years old and were currently prescribed timolol hemihydrate (once or twice da...

2017

Timolol maleate is a non-selective beta-adrenergic receptor blocking agent. Its chemical name is (-)-1-(tert-butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]-2-propanol maleate (1:1) (salt). Timolol maleate possesses an asymmetric carbon atom in its structure and is provided as the levo-isomer. The optical rotation of timolol maleate is: 25° [α] in 1.0N HCl (C = 5%) = -12.2° (-11.7° to -...

2014
Kenji Inoue Ryoko Okayama Risako Higa Goji Tomita

PURPOSE We prospectively investigated the intraocular pressure (IOP)-reducing effect, the visual field-maintenance effect, and the adverse reactions caused by administration of latanoprost/timolol maleate fixed-combination eyedrops for 3 years. SUBJECTS AND METHODS The subjects were 162 patients (162 eyes) with glaucoma or ocular hypotension who were using latanoprost and timolol maleate eyed...

2015
Hetain Patel Lina Vanessa Wilches Jorge Guerrero

Timolol maleate is a non-selective beta-adrenergic receptor blocking agent with demonstrated efficacy in the treatment of open-angle glaucoma. A 76 year old female who presented with productive cough, progressive dyspnea and hypoxia after starting timolol maleate opthalamic drops following glaucoma surgery. The patient was diagnosed with interstitial lung disease secondary to timolol treatment ...

2013
Mayur Patni Prashant Puranik Aravind Sonawane Prabhakar Panzade M. Patni P. Puranik A. Sonawane P. Panzade

Transdermal iontophoresis would be a promising method for the systemic delivery of water soluble and ionic drugs of relatively high molecular size, including peptides. The objective of the present study was to investigate the effect of biological variable such as guinea pig and human cadaver skin and other variables like drug concentration, current density on the transdermal iontophoretic trans...

Journal: :Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 2011
Noriaki Nagai Takatoshi Murao Kyouhei Oe Yoshimasa Ito Norio Okamoto Yoshikazu Shimomura

The combination of anti-glaucoma eye drops is frequently used in clinical treatment, and it is known that the combination can cause corneal damage. Recently, an anti-glaucoma combination eye drops is developed, and the treatment by the combination eye drops is expected to enhance quality of life. However, effects of the combination eye drops on corneal epithelial cell damage have not been clari...

2017
Hai Wei Wu Chao Liu Xuan Wang Ling Zhang Weien Yuan Jia Wei Zheng Li Xin Su Xin Dong Fan

The therapeutic options for infantile hemangiomas (IHs) have been greatly altered since the introduction of oral propranolol for successful treatments of IHs. Recently, there is an increase in the application of topical timolol maleate for treating superficial IHs. In the present study, we developed a new formulation of timolol maleate 0.5% hydrogel and treated 321 patients with superficial IHs...

Journal: :Contact dermatitis 2015
María Mercedes Otero-Rivas Inmaculada Ruiz-González Luis Miguel Valladares-Narganes Sonsoles Delgado-Vicente Manuel Ángel Rodríguez-Prieto

A 70-year-old man with glaucoma was treated with eyedrops containing timolol maleate and brimonidine tartrate for >2 years. The patient presented with erythematous and oedematous pruritic lesions on both cheeks (Fig. 1a). Patch testing was performed with the Spanish Contact Dermatitis Research Group baseline series (TRUE Test®; Stallergenes Ibérica, Madrid, Spain; Brial Allergens GmbH,Greven, G...

2012
Kenji Inoue Akira Setogawa Risako Higa Ryo Moriyama Masato Wakakura Goji Tomita

INTRODUCTION Travoprost 0.004%/timolol maleate 0.5% fixed combination eye drops are available in Japan. We prospectively investigated the intraocular pressure (IOP)-decreasing effect of travoprost 0.004%/timolol maleate 0.5% fixed combination eye drops and the adherence of patients to the administration protocol. MATERIALS AND METHODS We studied 43 eyes from 43 patients diagnosed with primary...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید