Background: Due to the lack of information about the role of 4G/5G polymorphism of PAI-1 Gene in susceptibility to thyroid tumors, this study was performed to evaluate the potential effects of this polymorphism on clinicopathologic features of thyroid tumors in Iranian Azeri Turkish patients. Methods:In this case-control study, 90 patients with thyroid tumors ...

abstract introduction: cancer stem cells are a small subpopulation of cells within a tumor which are responsible for maintaining the tumor mass. a number of factors such as oct-4 that govern the fate of adult stem cells also play a role in malignant cell transformation. oct-4 is a key regulator of self-renewal in embryonic stem cells; its expression is potentially correlated with tumorigenesis ...

In the blood of cancer patients, some nucleic acid fragments and tumor cells can be found that make it possible to trace tumor changes through a simple blood test called “liquid biopsy”. The main components of liquid biopsy are fragments of DNA and RNA shed by tumors into the bloodstream and circulate freely( ctDNAs and ctRNAs). tumor cells which are shed into the blood (circulating tumor cells...

Thyroid gland metastatic tumors are rare in clinical practice. Clear cell RCC is one of common metastatic tumors to thyroid. We here reported a case of incidentally found clear cell renal carcinoma metastasis to the thyroid gland 3 years after nephrectomy, in the thyroidectomy procedure performed for the patient due to the thyroid enlargement caused by multinodular goiter. A 65-year-old Iranian...

results there were 39 cases with lymph node metastasis in 59 malignant tumors, and 0 cases in 6 benign follicular type tumors. the staining scores by jt-95 of the 39 tumors with lymph node metastasis were 5+ in eight cases and 6+ in 31 cases. on the other hand, the scores of 20 malignant tumors without lymph node metastasis were < 4+ in all of the cases. in the co-cultured assay, numerous adhes...

metastasis to the oral region is very rare and accounts for less than 1% of oral malignant tumors. breast, lung, kidney, adrenal, gastro intestinal tract and prostates are most common primary tumors from which metastasis to oral region occur frequently. metastasis from thyroid gland is extremely rare to oral region. we present an unusual case of metastatic follicular carcinoma of thyroid in max...

Objective: The study evaluated the prevalence and progression of different thyroid tumors in patients who referred to Shahid Sadoughi Hospital during 2005 to 2013, Yazd, Iran. Materials and Methods: In this retrospective follow-up study, cytopathological data of patients suffering from thyroid masses was collected during 2005-2013. Age and sex of patients were recorded. Results: Totally, 2055...

radioiodine (1-131) is the treatment of choice in differentiated thyroid carcinoma. external radiotlierapy however, has it's own roie in these tumors. treatment of anaplastic thyroid carcinoma 1ms not acliieved any notahle success yet, though combined - modality regimens of radiotherapy and chemotherapy have sometimes shown significant results. in this paper the role of radiotlierapy and chemot...

  Radioiodine (1-131) is the treatment of choice in differentiated thyroid carcinoma. External radiotlierapy however, has it's own roie in these tumors. Treatment of anaplastic thyroid carcinoma 1ms not acliieved any notahle success yet, though combined - modality regimens of radiotherapy and chemotherapy have sometimes shown significant results. In this paper the rol...