Reports have shown the antioxidant, hypotensive, hypolipidemic and vasodilatory effects of grape (Vitis vinifera L.) seed extract. We have recently shown the relaxatory effect of grape leaf extract on rat uterus and reduction of frog heart rate and contractility. The aim of the present study was to investigate the relaxant effect of Vitis vinifera leaf hydroalcoholic extract (VLHE) on rat thora...

Reports have shown the antioxidant, hypotensive, hypolipidemic and vasodilatory effects of grape (Vitis vinifera L.) seed extract. We have recently shown the relaxatory effect of grape leaf extract on rat uterus and reduction of frog heart rate and contractility. The aim of the present study was to investigate the relaxant effect of Vitis vinifera leaf hydroalcoholic extract (VLHE) on rat thora...

reports have shown the antioxidant, hypotensive, hypolipidemic and vasodilatory effects of grape (vitis vinifera l.) seed extract. we have recently shown the relaxatory effect of grape leaf extract on rat uterus and reduction of frog heart rate and contractility. the aim of the present study was to investigate the relaxant effect of vitis vinifera leaf hydroalcoholic extract (vlhe) on rat thora...

Introduction: Our previous studies showed that hydroalcoholic extract of leaf of Vitis vinifera relaxes the phenylephrine-induced contraction in rat thoracic aorta. This effect was dependent on endothelial integrity and NO-cGMP system. The vasorelaxant effect of extract was much lesser on KCl-induced contraction. We, therefore, postulated that K+ channels are involved. The main aim of the pr...

introduction: our previous studies showed that hydroalcoholic extract of leaf of vitis vinifera relaxes the phenylephrine-induced contraction in rat thoracic aorta. this effect was dependent on endothelial integrity and no-cgmp system. the vasorelaxant effect of extract was much lesser on kcl-induced contraction. we, therefore, postulated that k+ channels are involved. the main aim of the prese...

Measurement of oxygen uptake by thoracic and abdominal segments of rat aorta showed significantly lower rates in the abdominal than in the thoracic aorta of adult animals. The evidence suggests that as a rat ages the respiratory rate of abdominal aorta falls more sharply than that of the thoracic segment. This result may provide an explanation for the relatively high incidence of atherosclerosi...

traumatic false aneurysm of the thoracic aorta is not uncommon. but accordingly this case is unusual in its ten year delay between injury and presentation and treatment. a victim of the iran-iraq war is presented with a false aneurysm of the thoracic aorta ten years after a bullet injury to the chest and thoracic spine. penetrating chest wounds, mechanisms of injury and diagnosis are also discu...

We tried to determine alpha 1-adrenoceptor subtypes involved in noradrenaline-induced contractions of rat thoracic aorta and dog carotid artery. Prazosin competitively antagonized the contractions induced by noradrenaline in both the arteries with a high pKB value (approximately 9.7). WB4101, benoxathian, phentolamine, HV723 and 5-methylurapidil also competitively antagonized the responses to n...

Traumatic false aneurysm of the thoracic aorta is not uncommon. But accordingly this case is unusual in its ten year delay between injury and presentation and treatment. A victim of the Iran-Iraq war is presented with a false aneurysm of the thoracic aorta ten years after a bullet injury to the chest and thoracic spine. Penetrating chest wounds, mechanisms of injury and diagnosis are also ...