This study aimed to develop controlled release formulation of Thiabendazole for reduced contaminations to soil water and agricultural produces. The idea behind this work was based on changing the ionization status of Thiabendazole molecule throughout pH changes to become a cation then adsorbing it to bentonite clay surfaces. Equilibrium concentrations of Thiabendazole in the adsorption solution...

In addition, cambendazole, but not thiabendazole or mebendazole, impaired the viability of S. ratti firstand second-stage larvae. The three drugs had no effect . Nov 4, 2016 . Thiabendazole was a therapeutic option for strongyloidiasis but has been discontinued. Albendazole and mebendazole have been used in patients with. For those too sick to tolerate or absorb oral (PO) ivermectin, rectal . J...

STATEMENT OF THE PROBLEM Evidence shows thiabendazole has the potential to inhibit angiogenesis in melanoma and fibrosarcoma; however, its effect on oral squamous cell carcinoma has not been previously studied. PURPOSE This study sought to assess the cytotoxic effects of thiabendazole on HN5 head and neck squamous carcinoma cell line. MATERIALS AND METHOD HN5 cell lines were exposed to diff...

BACKGROUND Strongyloidiasis may cause a life-threatening disease in immunosuppressed patients. This can only be prevented by effective cure of chronic infections. Direct parasitologic exams are not sensitive enough to prove cure if negative. We used an indirect immune fluorescent antibody test (IFAT) along with direct methods for patient inclusion and efficacy assessment. METHODOLOGY/PRINCIPA...

To evaluate the efficacy of thiabendazole for prophylaxis of strongyloidiasis in patients with hematologic diseases, we performed a randomized, placebo-controlled trial. The incidence of strongyloidiasis was similar in both groups (p=0.36), but the compliance was better in the placebo group (p=0.04). This study does not support the use of thiabendazole prophylaxis in patients with hematologic d...

The effects of in vitro incubation of three henzimidazole anthelmintics, thia­ bendazole, mebendazole and cambendazole on Strongyloides were compared. No drug affected hatching of S. ratti eggs or the viability of infective larvae or para­ sitic adult worms, but all three inhibited moulting of S. ratti larvae. In addition, cambendazole, but not thiabendazole or mebendazole, impaired the viabili...

Registered treatments for the control of avocado anthracnose caused by Colletotrichum goeosporioides are post-harvest applications of prochloraz and thiabendazole. Pre-harvest treatments to reduce inoculum levels in the field are also an important factor for successful anthracnose disease control. Pre-harvest application of benomyl was previously registered for this purpose, although at this st...

There is no consensus on the benefits of treatment with any specific anthelminthic compound on muscle-stage trichinosis. A double-blind, placebo-controlled comparison was done of 3 antiparasitic drugs during an outbreak of trichinosis in Chiangrai Province, northern Thailand. Forty-six adults were randomized to receive 10 days of oral treatment with mebendazole (200 mg twice a day), thiabendazo...

Fission yeast was treated with the anti-microtubule agent, thiabendazole. Cytoplasmic microtubules broke down with a half-time of less than 10 minutes followed closely by the unstacking of Golgi cisternae. The final product appeared to be single Golgi cisternae. No other organelle seemed to be affected by this treatment, which was completely reversible. The nda3 mutant strain has an altered bet...

Article history: Received on: 04/01/2013 Revised on: 19/01/2013 Accepted on: 01/02/2013 Available online: 27/2/2013 In this study a spectrofluorimetric method has been developed for determination of thiabendazole drug active compound in tablets. For this purpose; thiabendazole drug active compound was measured fluorescence intensities at excitation (ex) and emission (em) wavelength in various...