giant unilamellar vesicles (guvs) consisting in self-closed lipid bilayers of 0.5-100 µm diameter are considered as oversimplified models of cells because of their biological membrane and micrometric size while large unilamellar vesicles (luvs) of 100-500 nm diameter have applications in drug delivery. to improve structural and mechanical properties of these vesicles, we have developed two cate...

Harvesting cultivated macrophages for tissue engineering purposes by enzymatic digestion of cell adhesion molecules can potentially result in unintended activation, altered function, or behavior of these cells. Thermo-responsive polymer is a promising tool that allows for gentle macrophage detachment without artificial activation prior to subculture within engineered tissue constructs. We there...

Thermo-responsive adsorbents for immunoglobulin G (IgG) employing ε-polylysine (EPL) as a polymer backbone were developed. The introduction of mercaptoethylpyridine (MEP) as an IgG-binding ligand and hydrophobization of side chains afforded thermo-responsive IgG adsorbents, whose thermo-responsive IgG desorption ratio was up to 88% (EPL/MEP derivative 3m). The changes in surface densities of ac...

in this study, poly(ethylene-co-vinyl alcohol) (evoh) as a novel biocompatible polymeric scaffold was surface modified by succinylation to get evohs and further pegylated to improve structural properties using methoxypolyethylene glycol (5000 da) succinate (pegs) along with targeting with retinoic acid (ra) to get final modified active and passive targeted conjugate (pegs-evohs-ra) to evaluate ...

Non-invasive collection of target cells is crucial for research in biology and medicine. In this work, we combine a thermo-responsive material, poly(N-isopropylacrylamide), with an electroactive poly(3,4-ethylene-dioxythiopene):poly(styrene sulfonate), to generate smart conductive copolymer the label-free non-invasive detection capture release on gold electrodes by electrochemical impedance spe...

Biodegradable, stimuli-responsive polymers are essential platforms in the field of drug delivery and injectable biomaterials for application of bone tissue engineering. Various thermo-responsive hydrogels display water-based homogenous properties to encapsulate, manipulate and transfer its contents to the surrounding tissue, in the least invasive manner. The success of bioengineered injectable ...

Thermoresponsive TiO2/SiO2 one-dimensional photonic crystals (Bragg stacks) fabricated via sol–gel processing methods represent a promising class of environmentally responsive nanostructures featuring optically encoded temperature and humidity detection. The thermo-optic response of the layer materials is amplified by their inherent porosity owing to adsorption/desorption of ambient humidity in...