discussion we have to stress that the importance of this case report is its presentation in an elderly patient, as the frequent age of presentation in the iranian patients is the middle age. on the other hand, pv occurs rarely, thus, the reporting of any rare case with some exceptions is important. case presentation we reported a case of pemphigus vulgaris in a 79-year-old patient with the exte...

the classical etiology of erectile dysfunction (ed) comprises aging and vascular, neurogenic, psychological and hormonal components. recent studies have shown that ed can be the forerunner of serious cardiovascular disturbances. it has also been reported that peripheral neuropathy and microvascular injuries caused by pathophysiological changes in patients with diabetes and obesity lead to ed in...

background: â  advanced hepatic fibrosis and cirrhosis has generally been considered to be irreversible. the aim of this study was to determine whether cirrhosis is reversible.â  â  methods: â  seven patients with autoimmune hepatitis with histologic evidence of cirrhosis were enrolled. after treatment, they had follow-up liver biopsy while in clinical and biochemical remission. biopsy specimen...

cutaneous leishmaniasis is a common tropical dermatose with diverse clinical presentations. at times, it may appear in unusual shape or unusual site that causes diagnostic challenge. we reported a case of unusual presentation of cutaneous leishmaniasis which appeared as an ulcer on the lower lip of a ten-year-old boy. the diagnosis was confirmed by identifying leishmania parasites at ulcer smea...

background management of bacterial sepsis as a common cause of hospitalization and a life threatening clinical syndrome is a challenge. in previous studies, incorrect diagnosis of sepsis and unnecessary treatment have been frequently reported. objectives the aim of this study was to evaluate the diagnosis and treatment of cases with a primary diagnosis of sepsis. patients and methods of 410 med...

patients presenting with nephrotic syndrome with or without nephritic illness rarely come across with the diagnosis of ‘c1q nephropathy’. this entity is purely diagnosed with the help of immunofluorescence like iga nephropathy. clinical presentation is heterogenous, ranging from nephrotic range proteinuria to sub-nephrotic state; and with or without hematuria / renal insufficiency. similarly, t...

antifibrotic therapies should preferentially be targeted to the activated hepatic mesenchymal cells. those cells resemble wound healing myofibroblasts and synthesize an excess of extracellular matrix (ecm) proteins. they derive from quiescent hepatic stellate cells (hsc) and portal/perivascular (myo-) fibroblasts (mf). whereas various agents have been shown to inhibit hsc/mf proliferation and c...

orofacial granulomatosis(ofg) is a granulomatous disease of the orofacial region which appears usually as a persistent and/or recurrent labial soft tissues swelling in the orofacial region and is characterized histologically by a granulomatous inflammation. ofg may cause significant cosmetic and functional problems but can be prevented if the disease is diagnosed early and promptly treated. the...