Botulinum toxin (BoNT), being the most poisonous substance poses a great threat to global public health as a deadly bio-weapon. BoNT/A, BoNT/B and BoNT/E serotype toxicity cause flaccid paralysis in human by blocking neurotransmitter activity. Thearubigin, a black tea extract is found to be effective in neutralizing BoNT when experimented with animal models. This hypothesis opens a new frontier...

The botulinum neurotoxin produced by Clostridium botulinum exhibits the strongest neurotoxicity, and causes botulism in mammals. We have found an inactivator for clostridial neurotoxins in black tea extract (thearubigin fraction) as a natural foodstuff. In this study, we have isolated and identified the inactivators. The activity against the neuromuscular blocking action of botulinus neurotoxin...

Black tea has a lower antioxidant capacity than other teas, such as green tea, white and oolong tea. Tannase tyrosinase can be used treatment to improve the quality of black infusion. been reported an effective way enhance activity in Meanwhile, could produce higher theaflavin content thearubigin. Research about Ready-to-Drink (RTD) preparation with addition tannase fresh leaves before pasteuri...

(-)-Epicatechin (EC), (-)-epigallocatechin (EGC), (-)-epicatechin gallate (ECg), and (-)-epigallocatechin gallate (EGCg) were prepared from crude catechins (containing 90% cateehin in total) as described in our previous paper,i) Crude theaflavins, theafiavin (TFI), theaflavin monogallate A (TF2A), theafiavin monogallate B (TF2B), and theaflavin digallate (TF3) were prepared from black tea by ou...

the optimum fermentation times of black tea manufactured by two systems of orthodox and ctc (cut, tear & curl) were investigated by measuring the quality parameters of black tea, like: theaflavin, thearubigin, highly  polymerized substances and total liquid colour during the fermentation stage. optimum fermentation times from the beginning of fermentation were determined to be 60 min and 15...