hantzsch 1, 4-dihydropyridines (1,4-dhps) can be oxidized to the corresponding pyridine derivatives by thallium triacetate in high yields.

Hantzsch 1, 4-dihydropyridines (1,4-DHPs) can be oxidized to the corresponding pyridine derivatives by thallium triacetate in high yields.

The oxidation of 2-(3,4-dihydronaphthalen-1-yl)-ethanol (1) with a variety of thallium(III) salts was investigated. An indan, formed by a ring contraction reaction, was obtained in good to moderate yields under a variety of reaction conditions: i) thallium triacetate (TTA) in aqueous AcOH; ii) thallium tris-trifluoroacetate (TTFA) in aqueous TFA; iii) TTFA in CH(2)Cl(2); iv) thallium tripropion...

The indan skeleton is present in a variety of molecules with important biological activity, including the wellknown Indinavir and Aricept. Our research group has investigated approaches to obtain indans from 1,2dihydronaphthalenes, using a thallium(III)-promoted ring contraction reaction. During these studies, we found that a side chain at the double bond has a strong influence in the reaction ...

Fortisan, cellulose triacetate, and NOroxidized cellulose were pyrolyzed in a vacuum in the temperature range 1800 to 465 0 C. Cotton cellulose and cellulose t ri acetate were also pyrolyzed in nitrogen at atmospheric pressure. The tar yields were in the decreasing order from: Cotton, Fortisan, cellulose triacetate, and oxidized cellulose. The other volatiles consisted mainly of acetic acid, ca...

BACKGROUND Increased susceptibility to 5-fluorouracil (5-FU)/capecitabine can lead to rapidly occurring toxicity caused by impaired clearance, dihydropyrimidine dehydrogenase deficiency, and other genetic variations in the enzymes that metabolize 5-FU. Life-threatening 5-FU overdoses occur because of infusion pump errors, dosage miscalculations, and accidental or suicidal ingestion of capecitab...

A target value for iminoctadine triacetate residues in tap water was set at 6 microg/l in Japan. We have developed a highly selective and sensitive analytical method for iminoctadine triacetate by solid phase extraction LC/ESI/MS using hydrophilic interaction chromatography. The recovery rates at concentration of 0.06, 0.6, and 6 microg/l in distilled water, tap water, and raw water were 77.1 -...