An efficient synthesis of 1,3-thiazole drivatives is described via a three component reaction isothiocyanates, tetramethyl thiourea and ethyl bromopyruvate.

A convenient and efficient three-component reaction to a one-pot synthesis of thiophene derivatives from activated acetylenic compounds and ethyl 2chloroacetoacetate in the presence of tetramethyl thiourea in water lead to the formation of thiophenes in good yields.

A comparative DNA scission activity study of azaferrocene, N-methyl-azaferrocene iodide and 3,3',4,4'-tetramethyl-1,1'-diphosphaferrocene (featuring iron in a +2 oxidation state), along with ferrocene (iron +2) and ferrocenium (iron +3) cation is described. Experiments indicate a high cleavage activity of azaferrocene and its N-methyl derivative in DMSO. DNA cleavage activity can be slowed down...

In this research, a Brønsted acidic ionic liquid namely N1,N1,N2,N2-tetramethyl-N1,N2-bis(sulfo)ethane-1,2-diaminium chloride {[TMBSED][Cl]2} was employed as a highly efficient catalyst for the solvent-free production of some nitrogen- and oxygen-containing heterocyclic compounds including: (i) polyhydroquinolines (from arylaldehydes, dimedone, β-ketoesters and ammonium acetate), (ii) 3,4-dihyd...

We prepared and characterized a grinding-induced equimolar complex of thiourea with ethenzamide. When thiourea and ethenzamide were co-ground at a molar ratio of 3 : 1, new powder X-ray diffraction (PXRD) peaks were observed in addition to PXRD peaks of thiourea crystals. The optimum stoichiometry of the new structure was confirmed as 1 : 1 mol/mol. Effect of grinding time on the thiourea-ethen...

The reactive nitroxides 2,2,6,6-tetramethyl-1-oxyl-4-piperidyl chloroformate and 2,2,6,6-tetramethyl-1-oxyl-4-piperidyl chlorothionoformate were synthesized from 2,2,6,6-tetramethyl-4-hydroxypiperidin-1-oxyl and diphosgene (68%) or thiophosgene (61%), respectively. The reactions of the chloroformate and chlorothionoformate with lower secondary amines lead to 2,2,6,6-tetramethyl-1-oxyl-4-piperid...

A single bath full bleaching procedure for textile materials has been developed. In this procedure, following oxidative bleaching using hydrogen peroxide, the peroxide bath is converted to a reductive bath by addition of thiourea and bleaching continues without the need for a fresh bath for the reductive step. Such full bleaching is easy, economical and very effective in inducing improved white...

Thiourea (TU) application has been identified as a novel bioregulator technology, for imparting stress tolerance in crop plants. TU application has shown normal growth of Brassica juncea seedlings under salinity stress. In order to study the molecular mechanism underlying TU mediated response, genome wide transcriptome profiling of Brassica juncea seeds was undertaken. In one hour soaking time,...

Catalytic oxidation of thiourea has been studied at alumina modified Pt electrode using cyclic voltammetry. The results indicate the suitability of alumina modified Pt electrode for voltammetric determination of thiourea. The catalytic peak currents are linearly dependent on the thiourea concentration in the range 2.5 × 10 – 7.0 × 10 M. The usefulness of the method was tested in determination o...