Background: Polycystic ovary syndrome (PCOS) is a heterogeneous disease characterized by hyperandrogenaemia, hirsutism, oligo-or amenorrhea, and anovulation. A common feature of PCOS is the accumulation of small subcortical follicles and increased ovarian stromal volume, causing a characteristic ultrasound image and a basis for the most commonly used designation for the syndrome. In order to th...

Hormonally controlled differences in bone mineral density (BMD) between males and females are well studied. The effects of cross-sex hormones on bone metabolism in patients with early onset gender identity disorder (EO-GID), however, are unclear. We examined BMD, total body fat (TBF) and total lean body mass (TLBM) in patients prior to initiation of sex hormone treatment and during treatment at...

Fear can be considered as a functional defense behavior to protect living beings against dangerous situation. In our studies we have investigated the fear behavior in rats in elevated plus maze .The increase in two parameters percent of open arm entries (%OAE) and percent of time spent in the open arms (% OAT) and decrease in the percent of time spent in closed arm (%CAT) was considered as fear...

Fear can be considered as a functional defense behavior to protect living beings against dangerous situation. In our studies we have investigated the fear behavior in rats in elevated plus maze .The increase in two parameters percent of open arm entries (%OAE) and percent of time spent in the open arms (% OAT) and decrease in the percent of time spent in closed arm (%CAT) was considered as fear...

Background: Polycystic ovary syndrome (PCOS) is a multifactorial, heterogeneous, complex genetic endocrine and metabolic disorder, diagnostically characterized by chronic anovulation, polycystic ovaries and biochemical and clinical manifestations of hyperandrogenism. In patients with PCOS lower apoptotic rates found in granulosa cells compared to women with regular ovulatory cycles and this lea...

Depo-Provera® is depot medroxyprogesterone acetate (DMPA) aqueous suspension 150 mg in 1 ml formulated for deep IM injection. [2] This is most commonly used. Sayana Press® is DMPA 104 mg in 0.65 ml formulated for SC injection first licensed in the UK in 2011. [3] It is bio-equivalent to Depo-Provera®. It may be preferable to Depo-Provera® in women on anticoagulants or with a bleeding disorder. ...

The TMPRSS2 protein is an entry pathway for SARS-CoV-2, its expression up-regulated by testosterone. Men have 7 to 8 times higher serum testosterone than women. We propose that patients hospitalized with COVID-19, levels of testosterone, worse outcomes those lower levels.

androgenetic alopecia is the most common form of hair loss in men. the present study was designed to evaluate the hair growth-promoting activity of a preparation of the adiantum capillus veneris linn. (a. capillus veneris linn.) on albino mice using a testosterone-induced alopecia model. five groups of albino mice were studied: (a) testosterone solution only (n=6); (b) testosterone ‏+ finasteri...