background: it is proved that testis is sensitive to electromagnetic field (emf) and its damage results in infertility. exposure to emf induces reactive oxygen species production and affects on anti-oxidants defense mechanisms. metallothionein (mt) is a name for a group of low molecular weight (6-7 kda), sulfhydryl rich proteins. expression of mt1 and mt2 genes in testis tissue after emf exposu...

Objective: The local thermoregulation in testis is important for optimum spermatozoa development. Excessive heat hampers this regulation resulting alteration of normal testicular function. present investigation confirms the role free radicals hyperthermia induced oxidative damage and elucidates dose-dependent ameliorating effect resveratrol (RSV) against damage. aim also to observe selective co...

Abstract Background Genomic instability is a hallmark of various cancers, and DNA repair an essential process for maintaining genomic integrity. Mammalian cells have developed mechanisms in response to damage. Compared the cellular damage, vivo damage (DDR) specific tissues has not been studied extensively. Objective In this study, mice were exposed whole-body gamma (γ)-irradiation evaluate DDR...

Background: It is proved that testis is sensitive to electromagnetic field (EMF) and its damage results in infertility. Exposure to EMF induces reactive oxygen species production and affects on anti-oxidants defense mechanisms. Metallothionein (MT) is a name for a group of low molecular weight (6-7 kDa), sulfhydryl rich proteins. Expression of MT1 and MT2 genes in testis tissue after EMF exposu...

introduction: therapeutic strategies such as chemotherapy can affect gonadal adipose depots. the present study was conducted to assess stereological, morphometric and morphological changes in mouse testicular histoarchitecture structure following bilateral epididymal white adipose tissue lipectomy (biewatx) methods: in this experimental study, adult male mice were divided into three equal group...

introduction: the impact of chromium exposure was studied on liver, kidney, testis, spleen, cerebrum and cerebellum of male wistar rats (80-100 g body weight). material & method: it was observed that treatments of rats with chromium (i.p. at a dose of 0.8 mg / 100 g body weight per day) for a period of 28 days caused significant increase in chromium content while declining the body weight along...

Introduction: The impact of chromium exposure was studied on liver, kidney, testis, spleen, cerebrum and cerebellum of male Wistar rats (80-100 g body weight). Material & Method: It was observed that treatments of rats with chromium (i.p. at a dose of 0.8 mg / 100 g body weight per day) for a period of 28 days caused significant increase in chromium content while declining the body weight a...

Testicular damage is one of the most hazardous effects as it’s associated with azoospermia. Busulfan (Bu) a highly toxic chemotherapeutic drug that affects testis. Thirty male Swiss albino mice divided into six groups 5 animals each. Control (oral 0.9% saline daily for 75 days); Mel (20 mg/kg/day orally 30 ZnO NPs (5 i.p. BU (single injection 40 mg/kg and then left 45 + dose days followed by 20...

BACKGROUND Testicular torsion due to oxidative stress results in infertility and testicular damage which can be preventable an important health problem worldwide. AIM The purpose of the present study was to investigate the changes of malondialdehyde (MDA), total antioxidant status (TAS), total oxidant status (TOS) levels; histopathological alterations; morphology, concentration and motilities...