background: non obstructive azoospermia (noa) is one of the causes of male infertility in which spermatogenesis process is disturbed. recent studies suggested the possible role of endothelial nitric oxide synthase (enos) in spermatogenesis process. objective: the aim of the present study is to evaluate the expression of enos in human testicular tissue in men with noa and men with normal spermat...

objective: cryopreservation of immature testicular tissue should be considered as an important factor for fertility preservation in young boys with cancer. the objective of this study is to investigate whether immature testicular tissue of mice can be successfully cryopreserved using a simple vitrification procedure to maintain testicular cell viability, proliferation, and differentiation capac...

background: spermatogonial stem cells are subpopulation of spermatogonial cells in testis tissue that support beginning and maintenance of spermatogenesis. ubiquitin carboxy-terminal hydrolase l1 (uchl1) could be a specific marker for identification of spermatogonial stem cells including spermatogonial sperm cells (sscs) in testis tissue and during the culture; therefore we undertook this study...

background: testicular torsion and detorsion causes reperfusion injury which damages the testicular tissue and affects the quality of sperm. deterioration in the quality of sperm worldwide is the recent scenario and one of its reasons is testicular ischemic/ reperfusion (ir) injury. therefore the present study aims at producing new drugs for the treatment of testicular ir injury. methods: 42 an...

ÖZET Biyolojik dokuların vücut dışında canlılıklarını kaybetmeden yıllar boyunca saklanabilmesi kriyoprezervasyon aracılığıyla gerçekleştirilebilmektedir. Kriyoprezervasyon yoluyla dondurulacak hücreler, spermatogenezisi devam eden sağlıklı ve fertil hayvanlardan uygun metotlarla toplanarak elde edilebilmektedir. Günümüzde, erkek suni vajen, elektroejakülatör, el ile yapılan manipülasyonlar epi...

background: the aim of this study was to determine oxidative stress (os) parameters after testicular torsion/detorsion in adult rats. materials and methods: in this experimental study, male adult wistar rats were divided into four groups, each consisting of seven animals: group i-one hour right testicular torsion with subsequent orchiectomy, group ii-one hour right testicular torsion followed b...

Background: Ceftriaxone is an antibiotic used for treating respiratory,skin,bone and kidney infections. Our purpose was investigating effect of ceftriaxone on testicular tissue. Materials and Methods: 40 mice with 6 weeks old were used in this study. The mice randomly were divided into 2 groups, control- sham and test groups. The test group was subdivided to IP1 and IP2 which received Ceftriaxo...

BACKGROUND The xenografting of pre-pubertal human testicular tissue to an immunodeficient mouse is a theoretical strategy for restoring fertility in childhood cancer patients, while circumventing the risk of malignant recurrence. This study aimed at comparing the grafting of pre-pubertal and adult murine testicular tissue, as well as that of human adult testicular tissue, to two immunodeficient...