نتایج جستجو برای: Terazosin HCl

تعداد نتایج: 11695  

2013
L. M. Al-Harbi E. H. El-Mossalamy A. Y. Obaid M. A. EL-RIES

Thermal analysis of some antihypertensive drugs, Telmisartan, Cilazapril and Terazosin HCL was achieved. Thermogravimetry, derivative thermogravimetry and differential thermal analysis were used through the work. Thermogravimetric parameters such as activation energy, frequency factor and reaction order were calculated. The results show the stability value decrease in the order Telmisartan > Ci...

Journal: :iranian journal of pharmaceutical sciences 0
taghreed a. mohamed national organization for drug control and research, p.o. box 29, giza, cairo, egypt nahla s ismail national organization for drug control and research, p.o. box 29, giza, cairo, egypt

determination of terazosin hydrochloride dihydrate (trz) in drug substance and tablets was studied by fluorimetric techniques. the fluorimetric methods are based on: (1) measurement of the native fluorescence of the drug in water at 750 nm after excitation at 330 nm. (2) sensitizing the native fluorescence by formation a binary complex of drug with aqueous uranyl acetate (0.1% w/v) at the same ...

2013
Georgios Papadopoulos Dimitrios Vlachodimitropoulos Aspasia Kyroudi Mirsini Kouloukoussa Despina Perrea Dionisios Mitropoulos

BACKGROUND Quinazoline-based alpha1-adrenergic receptor antagonists may not act solely on smooth muscle contractility. We evaluated the in vivo effect of terazosin on the expression of caspase-3 in the rat ventral prostate. METHODS Fifteen Wistar rats were treated with terazosin (1.2 mg/kg body weight, given orally every second day) for 120 days. Another 15 control animals received the same a...

Journal: :The Journal of pharmacology and experimental therapeutics 1997
D G Witte M E Brune S P Katwala I Milicic J F Kerwin A A Hancock

The purpose of this study was to determine the potency and selectivity of the alpha-1 adrenergic receptor antagonist terazosin based on relationships between plasma concentrations and blockade of intraurethral pressure (IUP) and mean arterial pressure (MAP) responses after single dosing and to determine cumulative effects after repeated dosing. To this end, the relationships between plasma conc...

2014
Shujue Li Wenzheng Wu Weidong Ji Yeping Liang Lili Ou Guohua Zeng Wenqi Wu

Terazosin is one of classic quinazoline-based selective α1-adrenoreceptor antagonists, which is usually used for the treatment of benign prostate hyperplasia (BPH) patients. Several evidences suggest that terazosin can induce apoptosis of prostatic cancer cells in vitro and suppress prostatic tumor growth in vivo, but molecular mechanism contributing to these processes has not yet been fully el...

Journal: :Clinical and investigative medicine. Medecine clinique et experimentale 2009
Dionisios Mitropoulos Aspasia Kyroudi-Voulgari Evangelia Christelli Anastasios Zervas Panagiotis Karayannacos

PURPOSE Alpha1-adrenergic receptor antagonists may not act solely on smooth muscle contractility. We evaluated the in vivo effect of the alpha1 blocker, terazosin, on the expression of basic fibroblast growth factor (bFGF) in the rat ventral prostate. METHODS Wistar rats were treated with terazosin (1.2 mg/kg body weight, po, every second day) for 120 days. The expression of bFGF was assessed...

Journal: :Science-Business eXchange 2014

Journal: :Learning & memory 2010
Stephanie C Lazzaro Mian Hou Catarina Cunha Joseph E LeDoux Christopher K Cain

Norepinephrine receptors have been studied in emotion, memory, and attention. However, the role of alpha1-adrenergic receptors in fear conditioning, a major model of emotional learning, is poorly understood. We examined the effect of terazosin, an alpha1-adrenergic receptor antagonist, on cued fear conditioning. Systemic or intra-lateral amygdala terazosin delivered before conditioning enhanced...

2016
Shuangjian Jiang Chengqiang Mo Wei Sun Zeting Qiu Haiyi Long Wulin Tan Shaopeng Qiu Xiaopeng Mao

To provide a systematic review and network meta-analysis of randomized clinical trials focus on ejaculatory dysfunction (ED) rate of alpha blockers (ABs) for treatment of lower urinary tract symptoms (LUTS) in men with benign prostatic hyperplasia (BPH), a systematic literature search was performed to identify all available published randomized controlled trial (RCTs) as regards ABs for the tre...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید