نتایج جستجو برای: Targeted delivery

تعداد نتایج: 344312  

پایان نامه :دانشگاه آزاد اسلامی - دانشگاه آزاد اسلامی واحد تهران مرکزی - دانشکده علوم پایه 1391

one of the applications of nanotechnology is use of carbon nanotubes for the targeted delivery of drug molecules. to demonstrate the physical and chemical properties of biomolecules and identify new material of drug properties, the interaction of carbon nanotubes (cnts) with biomolecules is a subject of many investigations. cnts is a synthetic compound with extraordinary mechanical, thermal, el...

Journal: :iranian journal of pharmaceutical research 0
mehrdad hashemi associate of prod.,departmaent of genetics,iau,tehran medical branch fereshteh atabi department of biology, science and research branch, islamic azad university, tehran, iran seyed latif mousavi gargari department of biology, faculty of science, shahed university, tehran, iran parichehreh yaghmaei department of biology, science and research branch, islamic azad university, tehran, iran

recently, specific attention has been paid to aptamers, short dna or rna, as a tool for cancer diagnosis and therapy. in the present study mcs nanogels were prepared by myristate: chitosan at 1:9 ratio and were characterized by several techniques. a selected ssdna aptamer(apt) capable of detecting lncap cells was linked to myristilated chitosan nanogels (apt-mcs) by glutaraldehyde and loaded wi...

Journal: :nanomedicine research journal 0
pouya dehghankelishadi department of pharmaceutics, faculty of pharmacy, tehran university of medical sciences, tehran, iran farid dorkoosh department of pharmaceutics, faculty of pharmacy, tehran university of medical sciences, tehran, iran

pluronic based nano-particulate systems are innovative platforms for delivery of anti-cancer agents. these systems due to their pharmacological properties and suitable physicochemical characteristics are great opportunity for development cancer therapeutics. this mini-review tries to provide a more detailed overview on the currently available pluronic based drug delivery systems. in the section...

Journal: :the iranian journal of pharmaceutical research 0
bahram kazemi shahid beheshti university of medical sciences amir zarebkohan biomedical engineering and medical physics department, faculty of medicine, shahid beheshti university of medical sciences, tehran, iran farhood najafi department of resin and additives, institute for color science and technology, tehran, iran hamid reza moghimi school of pharmacy, shahid beheshti university of medical sciences, tehran, iran mohammad hemmati biomedical engineering and medical physics department, faculty of medicine, shahid beheshti university of medical sciences, tehran, iran mohammad reza deevband biomedical engineering and medical physics department, faculty of medicine, shahid beheshti university of medical sciences, tehran, iran

glioma, as a primary tumor of central nervous system, is the main cause of death in patients with brain cancer. therefore, development of an efficient strategy for treatment of glioma is worthy. the aim of the current study was to develop a srl peptide-coated dendrimer as a novel dual gene delivery system for targeting the lrp receptor, an up-regulated gene in both bbb and glioma cells. to perf...

Journal: :iranian journal of pharmaceutical research 0

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Journal: Nanomedicine Journal 2019
Hasanain Gomhor J. Alqaraghuli Kamran Mansouri, Ronak Rafipour, Soheila Kashanian,

Objective(s): Nanocarriers are drug delivery vehicles, which have attracted the attention of researchers in recent years, particularly in cancer treatment. The encapsulation of anticancer drugs using protein nanocages is considered to be an optimal approach to reducing drug side-effects and increasing the bioavailability of anticancer drugs. Epirubicin (EPR) is an active chemotherapeutic medica...

ژورنال: دانشور پزشکی 2012
اصل رسولی, نگار, احمدوند, داود , جعفری ایری سفلی, فرنوش , رهبری‌زاده, فاطمه ,

 Background and Objectives: The aim of this study was preparation of polyethyleneimine (PEI) nanoparticles targeted with anti-TAG72 nanobody for delivery of t-Bid gene construct into the human colonic adenocarcinoma cells. Materials and Methods: First of all, purified recombinant nanobody was verified by SDS-PAGE, western blotting and ELISA. Targeted polyplexes were constructed by reacting ...

Journal: :nanomedicine journal 0
mobin haghdel department of fluid mechanics, shiraz university, shiraz, iran reza kamali department of fluid mechanics, shiraz university, shiraz, iran ali haghdel department of electronics and communication engineering, shiraz university, shiraz, iran zahra mansoori department of physiology, shiraz university, shiraz, iran

objective(s): one applications of nanotechnology is in the area of medicine which is called nanomedicine. primary instruments in nanomedicine can help us to detect diseases and used for drug delivery to inaccessible areas of human tissues. an important issue in simulating the motion of nanoparticles is modeling blood flow as a newtonian or non-newtonian fluid. sometimes blood flow is simulated ...

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