Proteinak polimero lineal gisa sintetizatzen dira eta beren jatorrizko egitura tridimentsionalean tolestu behar zelulan hainbat funtzio betetzeko. Proteinen tolespena ulertzea funtsezkoa da, tolespen okerrak gaixotasun neuro-degeneratiboren jatorria direlako. modu koitzultzailean has daiteke, hau sortzen ari den peptidoa erribosomari lotuta dagoenean oraindik. Izan ere, zelularen proteinen here...

By the early 1990s, scientists knew that programmed cell death, or apoptosis, was important for tissue development and homeostasis as well as for cancer progression. Because apoptotic cells activate nucleases to cleave their chromatin, cell death could be followed in vitro by extracting DNA from a population of tissue culture cells and running it out on an agarose gel to look for a characterist...

purpose: to determine the maximum safe dose for intravitreal injection of anti-ctgf (ivac) in rat eyes in order to decrease gene and protein expression of connective tissue growth factor (ctgf) for the treatment of ocular fibrotic disorders. methods: forty-five lister hooded pigmented rats were divided into one of the five groups of 9 rats; 4 out of these 5 groups received different doses of iv...

background and objective: garlic has been known worldwide as a dietary constituent with many pharmacological effects. the present in vitro study was designed to investigate the putative anticancer effect of garlic extract on cancer cells, and if this effect was through apoptosis induction. material and methods:  human colon adenocarcinoma cells ht29 were treated with different doses (1, 5 and 1...

introduction: cisplatin is an anti-cancer drug used in chemotherapy. one of the limiting side effects of cisplatin is decreasing genital gland function, azoospermia and oligospermia. tribulus terrestris (tt) has been used as an aphrodisiac. the present study amid to investigate the protective effect of tt hydroalcoholic extract against cisplatin-induced apoptisis on testis in mice. methods: mal...