Streptococcus pyogenes can cause severe infections, such as toxic shock-like syndrome (TSLS). The transmission and pathogenesis of TSLS are poorly understood, and information is needed to develop prevention strategies. Four cases were identified in which the organism was transmitted among patients with TSLS and their family members. DNA macrorestriction endonuclease analysis using pulsed-field ...

OBJECTIVES/HYPOTHESIS To seek a correlation between the four types of transoral supraglottic laryngectomies (TSLs) according to the European Laryngological Society (ELS) and postoperative morbidity. STUDY DESIGN Retrospective case series at an academic institution. METHODS Chart review was done for 96 patients affected by T1-T3 supraglottic cancers (28 pT1, 46 pT2, 22 pT3) treated by TSL (2...

Article history: Received 7 May 2010 Received in revised form 13 September 2010 Accepted 18 September 2010 Claw lesions in lactating sows on 3 commercial farms were assessed in 6 areas of each of a sow's 8 claws to investigate the relationship between claw lesions and stage of lactation. In addition, the relationships between claw lesions and postural behavior, reproductive performance or culli...

A controversial technique for testing the hypothesis that physicians induce demand involves two stage least squares (TSLS) regression analysis of cross-section data on physician supply and utilization. This paper tests the power of TSLS by applying it where there is at most only a trivial amount of demand inducement--the demand for childbirths. We find 'evidence' of inducement of childbirths, c...

Toxic shock-like syndrome (TSLS) is characterized by hypotension or shock, fever, multiorgan system involvement, and a concurrent group A streptococcal infection. We analyzed 34 streptococcal strains isolated from patients with clinically well-documented TSLS for their pyrogenic toxin profiles and M-protein types. Although strains of nine different M types were represented in the sample, 74% of...

Acute respiration distress syndrome (ARDS) is a typical complication in toxic shock-like syndrome (TSLS) caused by Streptococcus pyogenes. An isolated perfused rat lung model was used to identify the causative agent of ARDS in TSLS in this study. Some crude preparations separated from the culture supernatants of S. pyogenes isolates caused rapid increases in the weight of perfused lungs, indica...

Theil, Basmann, and Sargan are often credited with the development of the two-stage least squares (TSLS) estimator of the coefficients of one structural equation in a simultaneous equations model. However, Anderson and Rubin had earlier derived the asymptotic distribution of the limited information maximum likelihood (LIML) estimator by finding the asymptotic distribution of what is essentially...

S treptococcus suis (S. suis) is widely recognised in the veterinary world as a cause of rapidly progressive and fatal sepsis in infant pigs, associated with meningitis, polyarthritis, and, occasionally, pneumonia. A more fulminant bacteraemic infection is seen in neonatal pigs [1,2]. For reasons that are unknown, adult pigs do not succumb to this infection, although they demonstrate asymptomat...

The possibility that a structural equation may not be identi...ed casts doubt on the measures of estimator precision that are normally used. We argue that the observed identi...ability test statistic is directly relevant to the precision with which the structural parameters can be estimated, and hence argue that inference in such models should be conditioned on the observed value of that statis...

A mental health trial is analyzed using a dose-response model, in which the number of sessions attended by the patients is deemed indicative of the dose of psychotherapeutic treatment. Here, the parameter of interest is the difference in causal treatment effects between the subpopulations that take part in different numbers of therapy sessions. For this data set, interactions between random tre...