background: the nutcracker syndrome represents a clinical condition caused by compression of the left renal vein (lrv) between the superior mesenteric artery (sma) and the aorta. one of its manifestations is left-sided varicocele. the aim of this study is to determine the prevalence of nutcracker syndrome in patients with primary and recurrent high grade left-sided varicocele.   methods: fifty ...

Novel lipid nanoparticulates (NCs) were developed by a combined approach of precipitation and complexation with an aim to improve the solubility, stability and targeting efficiency of glimepiride (GLP). GLP NCs were prepared by precipitation process using PEG 20000 and further complexed with phospholipon90G (P90G). The NCs were evaluated for physicochemical characterization, such as drug lo...

In the present work, a one pot, rapid and room temperature photochemical Synthesis of transition metal (TM; Cu, Mn, Cr)-doped ZnSe/ZnS core/shell nanocrystals (NCs) was reported. FT-IR spectrum confirmed the capping of ZnSe by thioglycolic acid. XRD and TEM analysis demonstrated zinc blende phase NCs with an average size of around 3 and 5 nm for TM:ZnSe and TM:ZnSe/ZnS NCs, respectively. PL spe...

The species HNCS and NCS have been studied by photoionization mass spectroscopy. The adiabatic ionization potential (IP) of HNCS is 69.92 eV, the shape of the ion yield.curve near threshold implies a large change in geometry, perhaps to linear HNCS+. Various appearance potentials (AP) from HNCS are determined by a more objective procedure, from which AH>(HNCS)>29.6 kcal/ mol (and very likely >3...

Background: The nutcracker syndrome represents a clinical condition caused by compression of the left renal vein (LRV) between the superior mesenteric artery (SMA) and the aorta. One of its manifestations is left-sided varicocele. The aim of this study is to determine the prevalence of nutcracker syndrome in patients with primary and recurrent high grade left-sided varicocele. Methods: Fifty pa...

The mode of neocarzinostatin-chromophore (NCS-chr)-apo-neocarzinostatin (apo-NCS) interaction in neocarzinostatin (NCS) complex has been described. The NCS-chr release from the NCS complex in the presence of various reagents, which destroy the high-order structure of the protein under various pH conditions, was examined. We found that (i) sodium dodecylsulfate, Nonidet P 40, 8 M urea, and 2-pro...

A series of heterobinuclear, thiocyanato-bridged complexes of cations [M(NH2X)6 ] 2+, and [M(en)3 ] 2+ (where X = H, Ph; M=Cu, Co, Cd, Zn) with anion [Ni(NCS)4 ] 2 –have been prepared by 1:1 molar ratio. The complexes have been characterized by FT-IR, 13C NMR and UV-vis spectroscopy, metal analysis, magnetic and conductance studies. The complexes have the following composition: [M(NH2 X)5 ][Ni(...

Neuronal calcium sensor-1 (NCS-1 Var1) is a calcium-binding protein expressed in most tissues. We examined a poorly characterized variant of NCS-1 (Var2), identified only in humans where the N-terminal 22 amino acid residues of native NCS-1(MGKSNSKLKPEVVEELTRKTY) were replaced with 4 different residues (MATI). Because alterations in the level of expression of NCS-1 Var1 and the expression of NC...

Streptomyces carzinostaticus produces the antitumor protein, NCS, and at the same time a related protein which antagonizes the antimicrobial effect of NCS. This has been designated pre-neocarzinostatin (pre-NCS). The physicochemical properties of pre-NCS are very close to those of NCS, except for a difference in isoelectric point. Production of pre-NCS in the culture filtrate precedes productio...