نتایج جستجو برای: TETRAPLOIDY

تعداد نتایج: 1945  

Journal: :Clinical genetics 2002
M Guc-Scekic J Milasin M Stevanovic L J Stojanov M Djordjevic

Liveborn infants with tetraploidy are very rare in human pregnancies and usually die during the first days or months. Seven cases of liveborn infants with tetraploidy have previously been reported. Among them only two 92, XXXX infants survived for longer than 12 months. Here we report on the case of a 26-month-old girl with tetraploidy. The main clinical features of tetraploidy are facial dysmo...

Journal: :Journal of medical genetics 1976
B S Danes

Tetraploidy was increased in skin fibroblast cultures grown in the laboratory at the same time under the same conditions and derived from 2 probands with the Gardner syndrome and 9 affected members of one family as compared to that occurring in cultures from 5 relatives by marriage and 10 normals. Tetraploidy was present at the first subculture (2 weeks after the initial biopsy was cultured), a...

Journal: :تحقیقات دامپزشکی 0
سالار درافشان گروه شیلات، دانشکده منابع طبیعی، دانشگاه صنعتی اصفهان، اصفهان–ایران امیر وفایی سعدی دانش آموخته، دانشکده منابع طبیعی دانشگاه صنعتی اصفهان، اصفهان–ایران علی نکوئی فرد موسسه تحقیقات علوم شیلاتی کشور، مرکز تحقیقات ژنتیک و اصلاح نژاد ماهیان سردآبی شهید مطهری یاسوج و مرکز مرجع آرتیما در منطقه میانی و غربی آسیا، ارومیه– ایران

background: tetraploid rainbow trout has a key role in producing infertile triploid fish by indirect method and introducing them in cultivation system. objectives: the purpose of the present study was to determine the optimal heat shock for tetraploidy induction in rainbow trout with emphasis on egg size. methods: the efficiency of different shock temperatures: 28, 30 and 32 °c, durations: 1, 5...

Journal: :Haematologica 2005
Zhijian Xiao Shihe Liu Xuping Liu Minghua Yu Yushu Hao

We report on 6 patients with tetraploidy or near-tetraploidy acute myeloid leukemia (AML) with double t(8;21) (q22;q22) and review the literature on cases with the same cytogenetic abnormalities. Some common features were revealed by this analysis.

2013
Laura Senovilla Ilio Vitale Isabelle Martins Oliver Kepp Lorenzo Galluzzi Laurence Zitvogel Maria Castedo Guido Kroemer

One of the driving forces of oncogenesis is tetraploidy, a duplication of the DNA content that, upon asymmetric cell division or progressive chromosome loss, can originate aneuploidy. Recent findings from our group indicate the existence of an immunosurveillance system that eliminates tetraploid cancer cells. We surmise that tetraploidy-inducing chemotherapeutic agents may elicit potent antican...

Journal: :Cancer research 2005
Katsuya Tsuchihara Valentina Lapin Christopher Bakal Hitoshi Okada Lauren Brown Masami Hirota-Tsuchihara Kathrin Zaugg Alexandra Ho Annick Itie-Youten Marees Harris-Brandts Robert Rottapel Christopher D Richardson Samuel Benchimol Tak Wah Mak

We used DNA microarray screening to identify Ckap2 (cytoskeleton associated protein 2) as a novel p53 target gene in a mouse erythroleukemia cell line. DNA damage induces human and mouse CKAP2 expression in a p53-dependent manner and p53 activates the Ckap2 promoter. Overexpressed Ckap2 colocalizes with and stabilizes microtubules. In p53-null cells, overexpression of Ckap2 induces tetraploidy ...

2016
Jitendra Kumar agrawal SureSh dinKar Kharche atul Saxena aKhil Patel Juhi PathaK anuJ Kumar Singh SiKarwar

| In vitro tetraploid embryo production has turn into an inestimable means in various research studies for researchers since last few years. The natural tetraploidy stage in embryo is exceptionally reported; hence different techniques have been engaged to bring the tetraploidy experimentally in mammals. There are three fundamental techniques to induce tetraploidy in vitro. First technique is th...

2004
Yumi Uetake

ailure of cells to cleave at the end of mitosis is dangerous to the organism because it immediately produces tetraploidy and centrosome amplification, which is thought to produce genetic imbalances. Using normal human and rat cells, we reexamined the basis for the attractive and increasingly accepted proposal that normal mammalian cells have a “tetraploidy checkpoint” that arrests binucleate ce...

Journal: :Proceedings of the National Academy of Sciences 1925

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